产品名称

英文名称：Albendazole Oxide

同义词

Albendazole oxide、Albendazole sulfoxide、Ricobendazole、54029-12-8、Albendazole S-oxide、Rycobendazole、Albendazole-sulfoxide、(+-)-Albendazole sulfoxide、Rycoben、RS 8852、methyl N-(6-propylsulfinyl-1H-benzimidazol-2-yl)carbamate、MFCD00797922、Methyl 5-(propylsulf、阿苯达唑亚砜

产品性质

CAS编号：54029-12-8

分子式：C12H15N3O3S

分子量：281.33

MDL号：MFCD00797922

PubChem编号：83969

别名：阿苯达唑亚砜

英文别名：Albendazole oxide|Albendazole sulfoxide|Ricobendazole|54029-12-8|Albendazole S-oxide|Rycobendazole|Albendazole-sulfoxide|(+-)-Albendazole sulfoxide|Rycoben|RS 8852|methyl N-(6-propylsulfinyl-1H-benzimidazol-2-yl)carbamate|MFCD00797922|Methyl 5-(propylsulf

规格或纯度：≥98%

英文名称：Albendazole Oxide

生化机理：Ricobendazole is a key metabolite of albendazole and acts as an anthelmintic. It has been shown to induce apoptosis in human cancer cell line HT-29, possibly by arresting cell cycle at the G2/M phase.Broad spectrum anthelmintic agent. Microtubule depolymerizing agent. Blood-brain barrier permeable active metabolite of Albendazole . Induces apoptosis and shows antitumor effects in vivo. Orally active.

运输条件：常规运输

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产品介绍：Albendazole Oxide 是一种微管蛋白聚合或装配抑制剂。Ricobendazole is a methylcarbamate benzimidazole with a broad-spectrum anthelmintic activity. Ricobendazole is a key metabolite of albendazole;It has been shown to induce apoptosis in human cancer cell line HT-29, possibly by arresting the cell cycle at the G2/M phase.Albendazole Oxide is a tubulin polymerization or assembly inhibitorRicobendazole is a methylcarbamate benzimidazole with a broad-spectrum anthelmintic activity. Ricobendazole is a key metabolite of albendazole;It has been shown to induce apoptosis in human cancer cell line HT-29, possibly by arresting the cell cycle at the G2/M phase.

PubChem SID：488186218

IUPAC Name：methyl N-(6-propylsulfinyl-1H-benzimidazol-2-yl)carbamate

INCHI：InChI=1S/C12H15N3O3S/c1-3-6-19(17)8-4-5-9-10(7-8)14-11(13-9)15-12(16)18-2/h4-5,7H,3,6H2,1-2H3,(H2,13,14,15,16)

InChi Key：VXTGHWHFYNYFFV-UHFFFAOYSA-N

Canonical SMILES：CCCS(=O)C1=CC2=C(C=C1)N=C(N2)NC(=O)OC

Isomeric SMILES：CCCS(=O)C1=CC2=C(C=C1)N=C(N2)NC(=O)OC

WGK Germany：3

PubChem CID：83969

溶解性：Soluble in DMSO (11 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C).

熔点：226 °C(dec.)

象形图：

信号词：Warning

危险声明：H373 Causes damage to organs through prolonged or repeated exposureH302 Harmful if swallowedH317 May cause an allergic skin reactionH400 Very toxic to aquatic lifeH410 Very toxic to aquatic life with long lasting effectsH361d Suspected of damaging the unborn childH371 May cause damage to organs

预防措施声明：P261,P273,P280,P302+P352,P321,P405,P501,P264,P260,P270,P272,P333+P313,P362+P364,P391,P330,P203,P301+P317,P318,P308+P316,P319

Merck Index：210

产品包装