产品名称

英文名称：8-Aminonaphthalene-1,3,6-trisulfonic acid disodium salt

同义词

5398-34-5、Disodium 8-amino-1,3,6-naphthalenetrisulfonate、ANTS、1,3,6-Naphthalenetrisulfonic acid, 8-amino-, disodium salt、1-Naphthylamine-3,6,8-trisulfonic acid disodium salt hydrate、8-Aminonaphthalene-1,3,6-trisulfonic acid disodium salt、8-Amino-1,3,6-nap、8-氨基萘-1,3,6-三磺酸二钠盐、8-氨基萘-1,3,6-三磺酸 二钠盐、8-氨基-1,3,6-萘三磺酸二钠

产品性质

CAS编号：5398-34-5

分子式：C10H7NNa2O9S3

分子量：427.34

Beilstein号：3854839

EC号：226-431-6

MDL号：MFCD00070572

PubChem编号：13152118

别名：8-氨基萘-1,3,6-三磺酸二钠盐|8-氨基萘-1,3,6-三磺酸 二钠盐|8-氨基-1,3,6-萘三磺酸二钠

英文别名：5398-34-5|Disodium 8-amino-1,3,6-naphthalenetrisulfonate|ANTS|1,3,6-Naphthalenetrisulfonic acid, 8-amino-, disodium salt|1-Naphthylamine-3,6,8-trisulfonic acid disodium salt hydrate|8-Aminonaphthalene-1,3,6-trisulfonic acid disodium salt|8-Amino-1,3,6-nap

规格或纯度：98%

英文名称：8-Aminonaphthalene-1,3,6-trisulfonic acid disodium salt

应用：A fluorescent label

储存温度：充氩

运输条件：常规运输

产品介绍：8-Aminonaphthalene-1,3,6-trisulfonic acid disodium salt is a fluorescent label for saccharides and glycoproteins, which is used in oligosaccharide sequencing and the study of membrane permeability and liposome lysis. ANTS has also been employed as a neuronal tracerA fluorescent label8-Aminonaphthalene-1,3,6-trisulfonic acid disodium salt is a fluorescent label for saccharides and glycoproteins, which is used in oligosaccharide sequencing and the study of membrane permeability and liposome lysis. ANTS has also been employed as a neuronal tracerA fluorescent labelapplicationThis molecular reagent is a polyanionic dye, which is often coupled with the cationic quencher DPX (X1525) for membrane fusion or permeability assays , including complement-mediated immune lysis. The fluorescence of ANTS has been shown to be effectively quenched by Thallium and Cesium ions. Utilized as a neuronal tracer. ANTS has a relatively high Stokes shift in water , which sufficiently separates its emission from the majority of the autofluorescence of biological samples. D2O increased the fluorescence quantum yield of ANTS four-fold, which has been demonstrated to be useful in the determination of water permeability in red blood cell ghosts and kidney collecting tubes . The reducing end of carbohydrates reacts with the primary amino group of the ANTS molecule, forming a Schiff base, which can then be reduced by sodium cyanoborohydride to a secondary amine. This reductive amination reaction is acid catalyzed, so the pH of the reaction solution can alter the kinetics and the degree of derivatization of the carbohydrate by ANTS. It is important to note this reaction is capable of proceeding at a neutral pH, which is favorable for the integrity of the sialic acid bonds in the oligosaccharide because they are sensitive to acid hydrolysis. Such labeling of carbohydrates with ANTS allows for complex mixtures to be separated via capillary electrophoresis .Fluorescent label for saccharides and glycoproteins used for oligosaccharide sequencing.

IUPAC Name：disodium;8-amino-6-sulfonaphthalene-1,3-disulfonate

INCHI：InChI=1S/C10H9NO9S3.2Na/c11-8-3-6(21(12,13)14)1-5-2-7(22(15,16)17)4-9(10(5)8)23(18,19)20;;/h1-4H,11H2,(H,12,13,14)(H,15,16,17)(H,18,19,20);;/q;2*+1/p-2

InChi Key：KHJANRFXWPPWEL-UHFFFAOYSA-L

Canonical SMILES：C1=C2C=C(C=C(C2=C(C=C1S(=O)(=O)O)N)S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+]

Isomeric SMILES：C1=C2C=C(C=C(C2=C(C=C1S(=O)(=O)O)N)S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+].[Na+]

WGK Germany：1

PubChem CID：13152118

Reaxy-Rn：3854839

密度：1.974

敏感性：对湿度和光线敏感

象形图：

信号词：Danger

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritationH318 Causes serious eye damage

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P305+P354+P338,P317,P337+P317,P332+P317,P319

个人防护装备：Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

产品包装