产品名称

英文名称：Racecadotril

同义词

Racecadotril、81110-73-8、Acetorphan、Benzyl 2-(3-(acetylthio)-2-benzylpropanamido)acetate、Hidrasec、Tiorfan、Racecadotril [INN]、Tiorfix、MFCD00865520、NSC-759828、benzyl (3-(acetylthio)-2-benzylpropanoyl)glycinate、76K53XP4TO、Racecadotril (INN)、benzyl 2-[[2-(acet、醋托泛、消旋卡多曲

产品性质

CAS编号：81110-73-8

分子式：C21H23NO4S

分子量：385.48

EC号：688-010-7

MDL号：MFCD00865520

PubChem编号：107751

别名：醋托泛|消旋卡多曲

英文别名：Racecadotril|81110-73-8|Acetorphan|Benzyl 2-(3-(acetylthio)-2-benzylpropanamido)acetate|Hidrasec|Tiorfan|Racecadotril [INN]|Tiorfix|MFCD00865520|NSC-759828|benzyl (3-(acetylthio)-2-benzylpropanoyl)glycinate|76K53XP4TO|Racecadotril (INN)|benzyl 2-[[2-(acet

规格或纯度：≥98%

英文名称：Racecadotril

生化机理：Racecadotril is a potent CD10 (enkephalinase) inhibitor which exhibits selective antisecretory activity.Potent enkephalinase inhibitor (IC 50 = 5 nM). Inhibits pathologic (but not basal) secretion from the gut. Shows blood-glucose lowering and central analgesic effects in vivo. Orally active.

应用：A potent enkephalinase inhibitor which exhibits selective antisecretory activity.

运输条件：常规运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Racecadotril 是一种外周性的脑啡肽酶抑制剂，IC50为4.5 μM。A potent enkephalinase inhibitor which exhibits selective antisecretory activity.Racecadotril is a peripherally acting enkephalinase inhibitor with an IC50 of 4.5 μM.A potent enkephalinase inhibitor which exhibits selective antisecretory activity.

ALogP：3.3

PubChem SID：488187417

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488187417

IUPAC Name：benzyl 2-[[2-(acetylsulfanylmethyl)-3-phenylpropanoyl]amino]acetate

INCHI：InChI=1S/C21H23NO4S/c1-16(23)27-15-19(12-17-8-4-2-5-9-17)21(25)22-13-20(24)26-14-18-10-6-3-7-11-18/h2-11,19H,12-15H2,1H3,(H,22,25)

InChi Key：ODUOJXZPIYUATO-UHFFFAOYSA-N

Canonical SMILES：CC(=O)SCC(CC1=CC=CC=C1)C(=O)NCC(=O)OCC2=CC=CC=C2

Isomeric SMILES：CC(=O)SCC(CC1=CC=CC=C1)C(=O)NCC(=O)OCC2=CC=CC=C2

WGK Germany：3

关联CAS：81110-73-8

PubChem CID：107751

NSC Number：759828

MeSH Entry Terms：acetorphan;acetorphan, (R)-isomer;acetorphan, (S)-isomer;ecadotril;N-(3-acetylmercapto-2-benzylpropanoyl)glycine benzyl ester;racecadotril;retorphan;sinorphan

CAS Registry No.：81110-73-8

溶解性：Soluble in ethanol (77 mg/ml at 25 °C), DMSO (≥44 mg/ml), and water (<1 mg/ml at 25 °C).

熔点：89 °C

象形图：

信号词：Warning

危险声明：H302 Harmful if swallowedH400 Very toxic to aquatic life

预防措施声明：P273,P501,P264,P270,P391,P330,P301+P317

Merck Index：8090

产品包装