产品名称

英文名称：Alendronic Acid

同义词

ALENDRONIC ACID、alendronate、66376-36-1、Fosamax、(4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid、Acido alendronico、Acide alendronique、Acidum alendronicum、Arendal、(4-Amino-1-hydroxybutane-1,1-diyl)diphosphonic acid、(4-Amino-1-hydroxybutylidene)bisphospho、4-氨基-1-羟基丁亚基-1,1-二磷酸

产品性质

CAS编号：66376-36-1

分子式：C4H13NO7P2

分子量：249.1

MDL号：MFCD00868112

PubChem编号：2088

别名：4-氨基-1-羟基丁亚基-1,1-二磷酸

英文别名：ALENDRONIC ACID|alendronate|66376-36-1|Fosamax|(4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid|Acido alendronico|Acide alendronique|Acidum alendronicum|Arendal|(4-Amino-1-hydroxybutane-1,1-diyl)diphosphonic acid|(4-Amino-1-hydroxybutylidene)bisphospho

规格或纯度：≥98.0%

英文名称：Alendronic Acid

运输条件：常规运输

产品介绍：Alendronate acid is an inhibitor of FDPS. It is a bisphosphonate that inhibits osteoclast-mediated bone resorption. Unlike pyrophosphate, the endogenous regulator of bone turnover to which it is chemically related, alendronate specifically inhibits osteoclastic osteoclastic bone resorption, having no effect on mineralization of bone newly formed by osteoblasts.An inhibitor of FDPSAlendronate acid is an inhibitor of FDPS. It is a bisphosphonate that inhibits osteoclast-mediated bone resorption. Unlike pyrophosphate, the endogenous regulator of bone turnover to which it is chemically related, alendronate specifically inhibits osteoclastic osteoclastic bone resorption, having no effect on mineralization of bone newly formed by osteoblasts.An inhibitor of FDPS

PubChem SID：488179658

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488179658

IUPAC Name：(4-amino-1-hydroxy-1-phosphonobutyl)phosphonic acid

INCHI：InChI=1S/C4H13NO7P2/c5-3-1-2-4(6,13(7,8)9)14(10,11)12/h6H,1-3,5H2,(H2,7,8,9)(H2,10,11,12)

InChi Key：OGSPWJRAVKPPFI-UHFFFAOYSA-N

Canonical SMILES：C(CC(O)(P(=O)(O)O)P(=O)(O)O)CN

Isomeric SMILES：C(CC(O)(P(=O)(O)O)P(=O)(O)O)CN

RTECS：SZ6521833

关联CAS：121268-17-5

PubChem CID：2088

Reaxy-Rn：2275403

DrugBank Ligand：DB00630

Wikipedia：Alendronic_acid

CAS Registry No.：66376-36-1

ChEMBL Ligand：CHEMBL870

RCSB PDB Ligand：212

PEP：alendronate

DrugCentral Ligand：112

熔点：235°C(dec.)(lit.)

象形图：

信号词：Danger

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH314 Causes severe skin burns and eye damageH302 Harmful if swallowedH318 Causes serious eye damageH290 May be corrosive to metalsH361 Suspected of damaging fertility or the unborn childH371 May cause damage to organs

预防措施声明：P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P260,P270,P301+P330+P331,P304+P340,P363,P362+P364,P330,P234,P390,P406,P203,P264+P265,P301+P317,P305+P354+P338,P318,P317,P337+P317,P308+P316,P332+P317,P302+P361+P354,P316

Merck Index：229

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