产品名称

英文名称：10-Deacetylbaccatin III

同义词

10-Deacetylbaccatin III、32981-86-5、10-Deacetylbaccatin、10-Deacetylbaccatine III、4K6EWW2Z45、CHEBI18193、10-Deacetyl baccatin III、10-O-Deacetylbaccatin III、10-DAB (10-Deacetylbaccatin)、5beta,20-epoxy-1,7beta,10beta,13alpha-tetrahydroxy-9-oxotax-11-ene-2alph、10-去乙酰基巴卡亭

产品性质

CAS编号：32981-86-5

分子式：C29H36O10

分子量：544.59

MDL号：MFCD00132913

PubChem编号：154272

别名：10-去乙酰基巴卡亭

英文别名：10-Deacetylbaccatin III|32981-86-5|10-Deacetylbaccatin|10-Deacetylbaccatine III|4K6EWW2Z45|CHEBI18193|10-Deacetyl baccatin III|10-O-Deacetylbaccatin III|10-DAB (10-Deacetylbaccatin)|5beta,20-epoxy-1,7beta,10beta,13alpha-tetrahydroxy-9-oxotax-11-ene-2alph

规格或纯度：95%

英文名称：10-Deacetylbaccatin III

生化机理：10-Deacetylbaccatin-III is an intermediate for taxol analog preparations. Taxols have exhibit antitumor agents. Several of these taxols can be synthesized from 10- Deacetylbaccatin-III. 10-Deacetylbaccine III is the fifth intermediate of paclitaxel biosynthesis. The biosynthetic pathway consists of approximately 20 enzymatic steps but is not fully elucidated. 10-Deacetylbaccine III is an antineoplastic agent and an anti-cancer intermediate.

应用：An intermediate for taxol analog preparations.

储存温度：2-8°C储存

运输条件：冰袋运输

备注：500mg卖完停产，不再备货

产品介绍：10-Deacetylbaccatin-III is an intermediate for taxol analog preparations. Taxols have exhibit antitumor agents. Several of these taxols can be synthesized from 10- Deacetylbaccatin-III.An intermediate for taxol analog preparations.10-Deacetylbaccatin-III is an intermediate for taxol analog preparations. Taxols have exhibit antitumor agents. Several of these taxols can be synthesized from 10- Deacetylbaccatin-III.An intermediate for taxol analog preparations.

PubChem SID：488188258

IUPAC Name：[(1S,2S,3R,4S,7R,9S,10S,12R,15S)-4-acetyloxy-1,9,12,15-tetrahydroxy-10,14,17,17-tetramethyl-11-oxo-6-oxatetracyclo[11.3.1.03,10.04,7]heptadec-13-en-2-yl] benzoate

INCHI：InChI=1S/C29H36O10/c1-14-17(31)12-29(36)24(38-25(35)16-9-7-6-8-10-16)22-27(5,23(34)21(33)20(14)26(29,3)4)18(32)11-19-28(22,13-37-19)39-15(2)30/h6-10,17-19,21-22,24,31-33,36H,11-13H2,1-5H3/t17-,18-,19+,21+,22-,24-,27+,28-,29+/m0/s1

InChi Key：YWLXLRUDGLRYDR-ZHPRIASZSA-N

Canonical SMILES：CC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1O)O)OC(=O)C5=CC=CC=C5)(CO4)OC(=O)C)O)C)O

Isomeric SMILES：CC1=C2[C@H](C(=O)[C@@]3([C@H](C[C@@H]4[C@]([C@H]3[C@@H]([C@@](C2(C)C)(C[C@@H]1O)O)OC(=O)C5=CC=CC=C5)(CO4)OC(=O)C)O)C)O

WGK Germany：3

PubChem CID：154272

Reaxy-Rn：1445248

溶解性：Soluble in DMSO (109 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), ethanol (<1 mg/ml at 25 °C), and chloroform.

密度：1.41

敏感性：对热敏感

比旋光度：-42° (C=1,MeOH)

熔点：231-236°C

象形图：

信号词：Danger

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritationH301 Toxic if swallowedH311 Toxic in contact with skinH331 Toxic if inhaledH373 Causes damage to organs through prolonged or repeated exposureH412 Harmful to aquatic life with long lasting effectsH340 May cause genetic defectsH350 May cause cancer

预防措施声明：P261,P305+P351+P338,P273,P280,P302+P352,P321,P405,P501,P264,P260,P281,P271,P270,P304+P340,P403+P233,P362+P364,P330,P361+P364,P203,P264+P265,P301+P316,P318,P337+P317,P332+P317,P316,P319

个人防护装备：Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

产品包装