产品名称

英文名称：Torcetrapib

同义词

BRD-K55675242-001-03-0、)-carboxylate、N-2790、CP-529414、s2792、TORCETRAPIB [MI]、AMY24146、1(2H)-Quinolinecarboxylic acid, 4-(((3,5-bis(trifluoromethyl)phenyl)methyl) (methoxycarbonyl)amino)-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-, ethyl ester, (2R,4S)-、托彻普

产品性质

CAS编号：262352-17-0

分子式：C26H25F9N2O4

分子量：600.47

MDL号：MFCD09260777

PubChem编号：159325

别名：托彻普

英文别名：BRD-K55675242-001-03-0|)-carboxylate|N-2790|CP-529414|s2792|TORCETRAPIB [MI]|AMY24146|1(2H)-Quinolinecarboxylic acid, 4-(((3,5-bis(trifluoromethyl)phenyl)methyl) (methoxycarbonyl)amino)-2-ethyl-3,4-dihydro-6-(trifluoromethyl)-, ethyl ester, (2R,4S)-

规格或纯度：≥98%

英文名称：Torcetrapib

生化机理：胆固醇酯转移蛋白（CETP）的抑制剂。还损害体内内皮功能；诱导高血压并抑制乙酰胆碱诱导的兔中耳动脉血管舒张。

法律信息：Sold for only research purposes

储存温度：2-8°C储存

运输条件：冰袋运输

备注：卖完停产，不再备货

产品介绍：Torcetrapib是一种CETP抑制剂，IC50为37 nM，提高血浆中HDL-C，降低nonHDL-C。Phase 3。A CETP inhibitor.Torcetrapib is a CETP inhibitor with IC50 of 37 nM, elevates HDL-C and reduces nonHDL-C in plasma. Phase 3.A CETP inhibitor.

IUPAC Name：ethyl (2R,4S)-4-[[3,5-bis(trifluoromethyl)phenyl]methyl-methoxycarbonylamino]-2-ethyl-6-(trifluoromethyl)-3,4-dihydro-2H-quinoline-1-carboxylate

INCHI：InChI=1S/C26H25F9N2O4/c1-4-18-12-21(19-11-15(24(27,28)29)6-7-20(19)37(18)23(39)41-5-2)36(22(38)40-3)13-14-8-16(25(30,31)32)10-17(9-14)26(33,34)35/h6-11,18,21H,4-5,12-13H2,1-3H3/t18-,21+/m1/s1

InChi Key：CMSGWTNRGKRWGS-NQIIRXRSSA-N

Canonical SMILES：CCC1CC(C2=C(N1C(=O)OCC)C=CC(=C2)C(F)(F)F)N(CC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)C(=O)OC

Isomeric SMILES：CC[C@@H]1C[C@@H](C2=C(N1C(=O)OCC)C=CC(=C2)C(F)(F)F)N(CC3=CC(=CC(=C3)C(F)(F)F)C(F)(F)F)C(=O)OC

WGK Germany：3

PubChem CID：159325

溶解性：溶于DMSO, 最高浓度 (mg/mL) 30.02, 最高浓度(mM) 50

象形图：

信号词：Warning

危险声明：H302 Harmful if swallowed

预防措施声明：P501,P264,P270,P330,P301+P317

产品包装