产品名称

英文名称：Methylene blue

同义词

Methylene Blue trihydrate、7220-79-3、Methylthionine chloride、C.I. Basic Blue 9 trihydrate、Phenothiazin-5-ium, 3,7-bis(dimethylamino)-, chloride, trihydrate、Basic Blue 9 trihydrate、3,7-Bis(dimethylamino)phenothiazin-5-ium chloride trihydrate、7220-79-3 (hdyr、次甲基蓝、次甲基兰、亚甲基兰、亚甲蓝

产品性质

CAS编号：7220-79-3

分子式：C16H18ClN3S·3H2O

分子量：373.9

Beilstein号：3599847

EC号：200-515-2

MDL号：MFCD00012111

PubChem编号：104827

别名：次甲基蓝|次甲基兰|亚甲基兰|亚甲蓝

英文别名：Methylene Blue trihydrate|7220-79-3|Methylthionine chloride|C.I. Basic Blue 9 trihydrate|Phenothiazin-5-ium, 3,7-bis(dimethylamino)-, chloride, trihydrate|Basic Blue 9 trihydrate|3,7-Bis(dimethylamino)phenothiazin-5-ium chloride trihydrate|7220-79-3 (hdyr

规格或纯度：用于生物学染色，Dye content, ≥90%(HPLC)

英文名称：Methylene blue

运输条件：常规运输

产品介绍：Methylene Blue acts as a GCS (guanylyl cyclase) inhibitor, biological stain and redox indicator. Methylene Blue inhibits tau filament formation. Additionally, Methylene Blue is also reported to inhibit NOSs (nitric oxide synthase). Methylene Blue is widely used to inhibit cGMP-mediated processes. Methylene Blue has been observed to dose-dependently induce cytotoxicity in U-373 MG human astrocytoma and SK-N-MC human neuroblastoma cells. Furthermore Methylene Blue is reported to bind to the M2 subtype of muscarinic receptors in rat cardiac myocytes, and thus exhibit antimuscarinic effects on IK, ACh and ICa. Methylene Blue has also been reported to inhibit endothelium-dependent relaxation of isolated blood vessels.An inhibitor of cGMP-mediated processes and guanylyl cyclase, a useful stain, and a redox indicatorMethylene Blue acts as a GCS (guanylyl cyclase) inhibitor, biological stain and redox indicator. Methylene Blue inhibits tau filament formation. Additionally, Methylene Blue is also reported to inhibit NOSs (nitric oxide synthase). Methylene Blue is widely used to inhibit cGMP-mediated processes. Methylene Blue has been observed to dose-dependently induce cytotoxicity in U-373 MG human astrocytoma and SK-N-MC human neuroblastoma cells. Furthermore Methylene Blue is reported to bind to the M2 subtype of muscarinic receptors in rat cardiac myocytes, and thus exhibit antimuscarinic effects on IK, ACh and ICa. Methylene Blue has also been reported to inhibit endothelium-dependent relaxation of isolated blood vessels.An inhibitor of cGMP-mediated processes and guanylyl cyclase, a useful stain, and a redox indicator

PubChem SID：488187373

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488187373

IUPAC Name：[7-(dimethylamino)phenothiazin-3-ylidene]-dimethylazanium;chloride;trihydrate

INCHI：InChI=1S/C16H18N3S.ClH.3H2O/c1-18(2)11-5-7-13-15(9-11)20-16-10-12(19(3)4)6-8-14(16)17-13;;;;/h5-10H,1-4H3;1H;3*1H2/q+1;;;;/p-1

InChi Key：XQAXGZLFSSPBMK-UHFFFAOYSA-M

Canonical SMILES：CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.O.O.O.[Cl-]

Isomeric SMILES：CN(C)C1=CC2=C(C=C1)N=C3C=CC(=[N+](C)C)C=C3S2.O.O.O.[Cl-]

WGK Germany：2

PubChem CID：104827

溶解性：Soluble in water (50 mg/ml), ethanol (70 mg/ml), alcohol, and chloroform. Insoluble in ether.

密度：1.14

熔点：235°C

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritationH373 Causes damage to organs through prolonged or repeated exposureH302 Harmful if swallowed

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P260,P271,P270,P304+P340,P403+P233,P362+P364,P330,P264+P265,P301+P317,P337+P317,P332+P317,P319

个人防护装备：Eyeshields,Faceshields,full-face respirator (US),Gloves,multi-purpose combination respirator cartridge (US),type ABEK (EN14387) respirator filter

产品包装