产品名称

英文名称：Dexmedetomidine HCl

同义词

Dexmedetomidine hydrochloride、145108-58-3、Dexmedetomidine HCL、Precedex、Dexdomitor、Cepedex、Sedadex、Dexdor、Sileo、IGALMI、Dexmedetomidine (hydrochloride)、(S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazole hydrochloride、UNII-1018WH7F9I、4-((S)-alpha,2,3-trimethyl、盐酸右美托咪定

产品性质

CAS编号：145108-58-3

分子式：C13H16N2·HCl

分子量：236.74

MDL号：MFCD12912677

PubChem编号：6918081

别名：盐酸右美托咪定

英文别名：Dexmedetomidine hydrochloride|145108-58-3|Dexmedetomidine HCL|Precedex|Dexdomitor|Cepedex|Sedadex|Dexdor|Sileo|IGALMI|Dexmedetomidine (hydrochloride)|(S)-5-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazole hydrochloride|UNII-1018WH7F9I|4-((S)-alpha,2,3-trimethyl

规格或纯度：≥98%

英文名称：Dexmedetomidine HCl

生化机理：Dexmedetomidine hydrochloride is a highly potent and selective α2-adrenergic agonist with analgesic and sedative properties, the (+)-isomer of medetomidine. Dexmedetomidine hydrochloride is used clinically as an anesthetic agent to reduce anxiety and tension and promote relaxation and sedation without causing respiratory depression.Potent, highly selective α 2 agonist. (K i values are 1.08 and 1750 nM at α 2 and α 1 receptors, respectively). Active enantiomer of medetomidine. Displays numerous actions including sedative, analgesic, anxiolytic, and antiulcerative propert

应用：An active isomer of medetomide, a potent and highly selective α2-adrenoceptor agonist.

储存温度：2-8°C储存

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Dexmedetomidine HCl 是一种有效的，高度选择性α-2肾上腺素受体激动剂，具有显著的镇静效果，从而降低患者的麻醉量。An active isomer of medetomide, a potent and highly selective α2-adrenoceptor agonist.Dexmedetomidine HCl is a highly selective and potent alpha-2 adrenoceptor agonist, which reduces anesthetic requirements for patients by providing significant sedation.An active isomer of medetomide, a potent and highly selective α2-adrenoceptor agonist.

IUPAC Name：5-[(1S)-1-(2,3-dimethylphenyl)ethyl]-1H-imidazole;hydrochloride

INCHI：InChI=1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H/t11-;/m0./s1

InChi Key：VPNGEIHDPSLNMU-MERQFXBCSA-N

Canonical SMILES：CC1=C(C(=CC=C1)C(C)C2=CN=CN2)C.Cl

Isomeric SMILES：CC1=C(C(=CC=C1)[C@H](C)C2=CN=CN2)C.Cl

WGK Germany：3

RTECS：NI5156750

PubChem CID：6918081

溶解性：Soluble in water (100 mM), DMSO (48 mg/ml), and ethanol (48 mg/ml).

敏感性：对热敏感

比旋光度：51° (C=1,H2O)

熔点：158 °C

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritationH302 Harmful if swallowed

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P403+P233,P362+P364,P330,P264+P265,P301+P317,P337+P317,P332+P317,P319

Merck Index：2946

产品包装