产品名称

英文名称：Rizatriptan Benzoate

同义词

Rizatriptan benzoate、145202-66-0、Maxalt、Maxalt-MLT、MK 462、Rizatriptan (benzoate)、MK-462、MK-0462、MK 0462、UNII-WR978S7QHH、WR978S7QHH、NSC-758919、RIZAFILM、2-(5-((1H-1,2,4-TRIAZOL-1-YL)METHYL)-1H-INDOL-3-YL)-N,N-DIMETHYLETHANAMINE BENZOATE、L 705126、L 705,126、L、利扎曲坦苯甲酸盐、苯甲酸利扎曲坦

产品性质

CAS编号：145202-66-0

分子式：C22H25N5O2

分子量：391.47

MDL号：MFCD00866224

PubChem编号：77997

别名：利扎曲坦苯甲酸盐|苯甲酸利扎曲坦

英文别名：Rizatriptan benzoate|145202-66-0|Maxalt|Maxalt-MLT|MK 462|Rizatriptan (benzoate)|MK-462|MK-0462|MK 0462|UNII-WR978S7QHH|WR978S7QHH|NSC-758919|RIZAFILM|2-(5-((1H-1,2,4-TRIAZOL-1-YL)METHYL)-1H-INDOL-3-YL)-N,N-DIMETHYLETHANAMINE BENZOATE|L 705126|L 705,126|L

规格或纯度：≥98%(HPLC)

英文名称：Rizatriptan Benzoate

生化机理：5-HT1B / 1激动剂。抗偏头痛药；减轻CGRP对小鼠避光的影响。口服具有生物活性。

应用：A selective serotonin 5-HTID receptor agonist.

运输条件：常规运输

备注：50mg、250mg卖完停产，不再备货

产品介绍：A selective serotonin 5-HTID receptor agonist.A selective serotonin 5-HTID receptor agonist.

IUPAC Name：benzoic acid;N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine

INCHI：InChI=1S/C15H19N5.C7H6O2/c1-19(2)6-5-13-8-17-15-4-3-12(7-14(13)15)9-20-11-16-10-18-20;8-7(9)6-4-2-1-3-5-6/h3-4,7-8,10-11,17H,5-6,9H2,1-2H3;1-5H,(H,8,9)

InChi Key：JPRXYLQNJJVCMZ-UHFFFAOYSA-N

Canonical SMILES：CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3.C1=CC=C(C=C1)C(=O)O

Isomeric SMILES：CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3.C1=CC=C(C=C1)C(=O)O

WGK Germany：3

PubChem CID：77997

溶解性：溶于water, 最高浓度 (mg/mL) 39.15, 最高浓度(mM) 100；溶于DMSO, 最高浓度 (mg/mL) 19.57, 最高浓度(mM) 50

熔点：180 °C

象形图：

信号词：Danger

危险声明：H319 Causes serious eye irritationH302 Harmful if swallowedH336 May cause drowsiness or dizzinessH372 Causes damage to organs through prolonged or repeated exposureH360 May damage fertility or the unborn childH361 Suspected of damaging fertility or the unborn childH361d Suspected of damaging the unborn child

预防措施声明：P261,P305+P351+P338,P280,P405,P501,P264,P260,P271,P270,P304+P340,P403+P233,P330,P203,P264+P265,P301+P317,P318,P337+P317,P319

Merck Index：8241

产品包装