产品名称

英文名称：Inosine 5′-triphosphate trisodium salt

同义词

35908-31-7、Inosine-5'-triphosphate trisodium salt、Inosine 5'-triphosphate trisodium salt、Inosine 5' Triphosphate Trisodium Salt、ITP、trisodium;[[[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hy、ITP、5'-三磷酸肌苷钠盐、肌苷5'-三磷酸三钠盐、特发性血小板减少性紫癜

产品性质

CAS编号：35908-31-7

分子式：C10H12Na3N4O14P3

分子量：574.11

MDL号：MFCD00084678

PubChem编号：135742691

别名：ITP|5'-三磷酸肌苷钠盐|肌苷5'-三磷酸三钠盐|特发性血小板减少性紫癜

英文别名：35908-31-7|Inosine-5'-triphosphate trisodium salt|Inosine 5'-triphosphate trisodium salt|Inosine 5' Triphosphate Trisodium Salt|ITP|trisodium;[[[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hy

规格或纯度：96%

英文名称：Inosine 5′-triphosphate trisodium salt

生化机理：肌苷 5′——三磷酸盐 (ITP) 具有支持效应系统启动的能力。可阻止鸟苷 5′——三磷酸鸟苷 (GTP) 水解，由转导素 (TD) 催化。与 GTP 相比，ITP 能熟练诱导透化细胞分泌。ITP 代替 GTP 可用于呼肠孤病毒转录的起始和延伸步骤。ITP 在 G 蛋白的激活中也能取代 GTP。

应用：Inosine 5′-triphosphate (ITP) is used in studies on the impact of deamination of ATP and GTP by various enzymes and chemical processes. ITP may be used as a substrate to study the specificity and kinetics of nucleoside-5′-triphosphatase and ATPase. ITP is also used to study activation of various ATPases and GTPases. Inosine 5′-triphosphate trisodium salt has been used to investigate its influence on the chromosome aberration rate, the mitotic rate, sister-chromatid exchange (SCE) frequency, the proportion of first (X1), second (X2) and third (X3) division metaphases of human peripheral lymphocytes.

储存温度：-20°C储存,充氩

运输条件：超低温冰袋运输

产品介绍：产品应用肌苷 5′-三磷酸盐 (ITP) 用于各种酶和化学过程对 ATP 和 GTP 脱氨作用影响的研究。ITP 可作为研究核苷-5′ 的特异性和动力学的底物-三磷酸酶和 atp 酶。ITP 也用于研究各种 atp 酶和 gtp 酶的激活。Inosine 5′-triphosphate (ITP) is used in studies on the impact of deamination of ATP and GTP by various enzymes and chemical processes. ITP may be used as a substrate to study the specificity and kinetics of nucleoside-5′-triphosphatase and ATPase. ITP is also used to study activation of various ATPases and GTPases.

IUPAC Name：trisodium;[[[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-1H-purin-9-yl)oxolan-2-yl]methoxy-oxidophosphoryl]oxy-oxidophosphoryl] hydrogen phosphate

INCHI：InChI=1S/C10H15N4O14P3.3Na/c15-6-4(1-25-30(21,22)28-31(23,24)27-29(18,19)20)26-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17;;;/h2-4,6-7,10,15-16H,1H2,(H,21,22)(H,23,24)(H,11,12,17)(H2,18,19,20);;;/q;3*+1/p-3/t4-,6-,7-,10-;;;/m1.../s1

InChi Key：QRGLCGLOQVQVCS-MSQVLRTGSA-K

Canonical SMILES：C1=NC2=C(C(=O)N1)N=CN2C3C(C(C(O3)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O)O.[Na+].[Na+].[Na+]

Isomeric SMILES：C1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)([O-])OP(=O)([O-])OP(=O)(O)[O-])O)O.[Na+].[Na+].[Na+]

WGK Germany：1

PubChem CID：135742691

溶解性：Methanol (Very Slightly, Heated), Water (Slightly)

敏感性：对热敏感;对湿度敏感

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritation

预防措施声明：P305+P351+P338,P280,P302+P352,P321,P264,P362+P364,P264+P265,P337+P317,P332+P317

产品包装