产品名称

英文名称：Levofloxacin

同义词

LEVOFLOXACIN、100986-85-4、Levaquin、Quixin、(-)-Ofloxacin、Cravit、Iquix、Tavanic、Ofloxacin S-(-)-form、Levofloxacine、(S)-Ofloxacin、L-Ofloxacin、Levofloxacino、Levofloxacinum、Elequine、Oftaquix、Levofloxacin Anhydrous、Floxacin、Volequin、Nofaxin、(S)-(-)-Ofloxacin、DR-3、左氧氟沙星

产品性质

CAS编号：100986-85-4

分子式：C18H20FN3O4

分子量：361.37

MDL号：MFCD00865049

PubChem编号：149096

别名：左氧氟沙星

英文别名：LEVOFLOXACIN|100986-85-4|Levaquin|Quixin|(-)-Ofloxacin|Cravit|Iquix|Tavanic|Ofloxacin S-(-)-form|Levofloxacine|(S)-Ofloxacin|L-Ofloxacin|Levofloxacino|Levofloxacinum|Elequine|Oftaquix|Levofloxacin Anhydrous|Floxacin|Volequin|Nofaxin|(S)-(-)-Ofloxacin|DR-3

规格或纯度：>98.0%(HPLC)

英文名称：Levofloxacin

生化机理：Levofloxacin is active against Gram-positive and Gram-negative bacteria. It inhibits DNA gyrase (type II topoisomerase) and topoisomerase IV, thereby inhibiting cell division.Fluoroquinolone antibiotic. Effective against Gram-positive and Gram-negative bacteria. Pharmacologically active following oral administration. Crosses the blood-brain barrier.

储存温度：2-8°C储存

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Levofloxacin is a broad-spectrum antibiotic used in pharmacokinetic , antibiotic resistance , and resistance prevention studies. Antibiotic against bacterial respiratory tract infections.Levofloxacin is a broad-spectrum antibiotic used in pharmacokinetic , antibiotic resistance , and resistance prevention studies. Antibiotic against bacterial respiratory tract infections.

IUPAC Name：(2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid

INCHI：InChI=1S/C18H20FN3O4/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21/h7-8,10H,3-6,9H2,1-2H3,(H,24,25)/t10-/m0/s1

InChi Key：GSDSWSVVBLHKDQ-JTQLQIEISA-N

Canonical SMILES：CC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O

Isomeric SMILES：C[C@H]1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O

RTECS：UU8815550

PubChem CID：149096

Reaxy-Rn：5385660

RCSB PDB Ligand：LFX

CAS Registry No.：100986-85-4

DrugBank Ligand：DB01137

ChEMBL Ligand：CHEMBL33

DrugCentral Ligand：1569

Antibiotic DB：2026

溶解性：Slightly soluble in water or methanol. Soluble in glacial acetic acid or dichloromethan

敏感性：对光线敏感

比旋光度：-66° (C=5,CHCl3)

熔点：224 °C

象形图：

信号词：Danger

危险声明：H302 Harmful if swallowedH317 May cause an allergic skin reactionH334 May cause allergy or asthma symptoms or breathing difficulties if inhaledH361 Suspected of damaging fertility or the unborn childH362 May cause harm to breast-fed children

预防措施声明：P261,P280,P302+P352,P321,P405,P501,P264,P260,P284,P270,P304+P340,P272,P333+P313,P362+P364,P330,P263,P203,P301+P317,P318,P342+P316

Merck Index：6771

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