产品名称

英文名称：Amlodipine besylate

同义词

AMLODIPINE BESYLATE、111470-99-6、Norvasc、Amlodipine benzenesulfonate、Amlodipine besilate、Monopina、Antacal、Istin、Amlogard、Cordarene、Norlopin、Tensivask、Amcard、Amdepin、Amdipin、Amlodin、Amlopin、Amlosyn、Astudar、Myodura、Norvas、Norvask、Pelmec、Terloc、Amlodipine (be、阿罗地平磺酸盐

产品性质

CAS编号：111470-99-6

分子式：C20H25ClN2O5·C6H5SO3H

分子量：567.05

MDL号：MFCD00887594

PubChem编号：60496

别名：阿罗地平磺酸盐

英文别名：AMLODIPINE BESYLATE|111470-99-6|Norvasc|Amlodipine benzenesulfonate|Amlodipine besilate|Monopina|Antacal|Istin|Amlogard|Cordarene|Norlopin|Tensivask|Amcard|Amdepin|Amdipin|Amlodin|Amlopin|Amlosyn|Astudar|Myodura|Norvas|Norvask|Pelmec|Terloc|Amlodipine (be

规格或纯度：98%

英文名称：Amlodipine besylate

生化机理：强大的L型钙通道阻滞剂。抑制Ca 2+引起的收缩（IC 50 = 2 nM）。显示出抗增殖作用。在体内显示出降压作用。口服具有活性

应用：Amlodipine besylate is a L-type calcium channel blocker which may be used for the treatment of angina pectoris and hypertension. Amlodipine also inhibits growth of human epidermoid carcinoma A431 cells and has antireproductive effects in male rats

运输条件：常规运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：相关CAS编码 88150-42-9Amlodipine besylate is a L-type calcium channel blocker which may be used for the treatment of angina pectoris and hypertension. Amlodipine also inhibits growth of human epidermoid carcinoma A431 cells and has antireproductive effects in male ratsRelated CAS Number 88150-42-9Amlodipine besylate is a L-type calcium channel blocker which may be used for the treatment of angina pectoris and hypertension. Amlodipine also inhibits growth of human epidermoid carcinoma A431 cells and has antireproductive effects in male rats.

IUPAC Name：benzenesulfonic acid;3-O-ethyl 5-O-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate

INCHI：InChI=1S/C20H25ClN2O5.C6H6O3S/c1-4-28-20(25)18-15(11-27-10-9-22)23-12(2)16(19(24)26-3)17(18)13-7-5-6-8-14(13)21;7-10(8,9)6-4-2-1-3-5-6/h5-8,17,23H,4,9-11,22H2,1-3H3;1-5H,(H,7,8,9)

InChi Key：ZPBWCRDSRKPIDG-UHFFFAOYSA-N

Canonical SMILES：CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.C1=CC=C(C=C1)S(=O)(=O)O

Isomeric SMILES：CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN.C1=CC=C(C=C1)S(=O)(=O)O

WGK Germany：3

RTECS：US7967700

PubChem CID：60496

Reaxy-Rn：8378713

溶解性：Soluble in DMSO (≥20 mg/mL), water (10 mM), chloroform, ethanol (≥14 mg/mL), and methanol

熔点：195-204°C

象形图：

信号词：Danger

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritationH411 Toxic to aquatic life with long lasting effectsH302 Harmful if swallowedH318 Causes serious eye damageH400 Very toxic to aquatic lifeH332 Harmful if inhaledH410 Very toxic to aquatic life with long lasting effectsH361d Suspected of damaging the unborn child

预防措施声明：P261,P305+P351+P338,P273,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P403+P233,P362+P364,P391,P330,P203,P264+P265,P301+P317,P305+P354+P338,P318,P317,P337+P317,P332+P317,P319

Merck Index：491

个人防护装备：dust mask type N95 (US), Eyeshields, Faceshields, Gloves

产品包装