产品名称

英文名称：Hexaminolevulinate hydrochloride

同义词

140898-91-5、Hexaminolevulinate Hydrochloride、Hexyl 5-amino-4-oxopentanoate hydrochloride、5-Aminolevulinic acid hexyl ester hydrochloride、hexaminolevulinate HCl、Cysview、Hexvix、HexvisR、Hexaminolevulinate (hydrochloride)、P-1206、Cysview Kit、UNII-D4F329SL1O、D4、5-氨基酮戊酸己酯盐酸盐

产品性质

CAS编号：140898-91-5

分子式：C11H21NO3· HCl

分子量：251.75

MDL号：MFCD03695491

PubChem编号：6433082

别名：5-氨基酮戊酸己酯盐酸盐

英文别名：140898-91-5|Hexaminolevulinate Hydrochloride|Hexyl 5-amino-4-oxopentanoate hydrochloride|5-Aminolevulinic acid hexyl ester hydrochloride|hexaminolevulinate HCl|Cysview|Hexvix|HexvisR|Hexaminolevulinate (hydrochloride)|P-1206|Cysview Kit|UNII-D4F329SL1O|D4

规格或纯度：98%

英文名称：Hexaminolevulinate hydrochloride

生化机理：Hexaminolevulinate (HAL) hydrochloride is a hexyl ester of 5-Aminolevulinic acid (ALA), a precursor to porphyrins including the photosensitizer protoporphyrin IX (PPIX). Hexaminolevulinate is more lipophilic than ALA, and is 50–100 times more efficient than ALA at inducing PpIX, which accumulates preferentially in neoplastic cells. Hexaminolevulinate administration followed by light activation has been used for fluorescence cystoscopy to enhance detection of bladder cancer, in particular carcinoma in situ (CIS). Hexaminolevulinate is also being studied for use in cancer photodynamic therapy. Hexaminolevulinate followed by irradiation produced DNA oxidative damage and apoptosis.

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：Hexaminolevulinate盐酸盐是一种荧光剂, 已批准用于膀胱镜检测乳头状膀胱癌。Hexaminolevulinate hydrochloride is a fluorescent agent, has approved for cystoscopic detection of papillary bladder cancer.

IUPAC Name：hexyl 5-amino-4-oxopentanoate;hydrochloride

INCHI：InChI=1S/C11H21NO3.ClH/c1-2-3-4-5-8-15-11(14)7-6-10(13)9-12;/h2-9,12H2,1H3;1H

InChi Key：LZYXPFZBAZTOCH-UHFFFAOYSA-N

Canonical SMILES：CCCCCCOC(=O)CCC(=O)CN.Cl

Isomeric SMILES：CCCCCCOC(=O)CCC(=O)CN.Cl

PubChem CID：6433082

溶解性：H2O 20 mg/mL, clear;DMSO ≥ 41 mg/mL (162.86 mM)

敏感性：对湿度敏感

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritationH317 May cause an allergic skin reaction

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P272,P333+P313,P362+P364,P264+P265,P337+P317,P332+P317,P319

产品包装