产品名称

英文名称：Phloretin

同义词

phloretin、60-82-2、Dihydronaringenin、3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one、Phloretol、3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone、NSC 407292、1-Propanone, 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-、MFCD00002288、beta-(、3-(4-羟苯基)-1-(2,4,6-三羟基苯基)-1-丙酮、3-(4-羟苯基)-1-(2,4,6-三羟基苯基)-1-丙酮

产品性质

CAS编号：60-82-2

分子式：C15H14O5

分子量：274.27

Beilstein号：1887240

EC号：200-488-7

MDL号：MFCD00002288

PubChem编号：4788

别名：3-(4-羟苯基)-1-(2,4,6-三羟基苯基)-1-丙酮|3-(4-羟苯基)-1-(2,4,6-三羟基苯基)-1-丙酮

英文别名：phloretin|60-82-2|Dihydronaringenin|3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one|Phloretol|3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone|NSC 407292|1-Propanone, 3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-|MFCD00002288|beta-(

规格或纯度：≥98%

英文名称：Phloretin

生化机理：Phloretin is an inhibitor of calcium channel protein, MCT1, MCT2, and PKC. It is the major polyphenol found in apple.Dihydrochalcones flavonoid. GLUT inhibitor. Active phlorizin metabolite. Blocks L-type Ca 2+ channels. Activates Ca 2+ -activated K + channels. Inhibits platelet aggregation. Induces apoptosis. Shows antitumor effects in vivo . Orally active.

应用：A calcium channel protein inhibitor.

储存温度：2-8°C储存

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Phloretin 是一种二氢查尔酮，含有多元酚。A calcium channel protein inhibitor.Phloretin is a dihydrochalcone found in apple tree leaves, which shows beneficial effects on diabetes.A calcium channel protein inhibitor.

IUPAC Name：3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)propan-1-one

INCHI：InChI=1S/C15H14O5/c16-10-4-1-9(2-5-10)3-6-12(18)15-13(19)7-11(17)8-14(15)20/h1-2,4-5,7-8,16-17,19-20H,3,6H2

InChi Key：VGEREEWJJVICBM-UHFFFAOYSA-N

Canonical SMILES：C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O)O)O)O

Isomeric SMILES：C1=CC(=CC=C1CCC(=O)C2=C(C=C(C=C2O)O)O)O

WGK Germany：3

PubChem CID：4788

Reaxy-Rn：1887240

DrugBank Ligand：DB07810

Wikipedia：Phloretin

CAS Registry No.：60-82-2

ChEBI：CHEBI17276

ChEMBL Ligand：CHEMBL45068

BitterDB Ligand：909

RCSB PDB Ligand：G50

溶解性：Soluble in ethanol, methanol, acetone, hot glacial acetic acid, alkalies, benzene (sparingly soluble), chloroform (sparingly soluble), and DMSO. Insoluble in water, and ether.

敏感性：对热和光线敏感

熔点：262°C

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritation

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319

Merck Index：7326

个人防护装备：Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

产品包装