产品名称

英文名称：α-Chymotrypsin from bovine pancreas

同义词

Chymotrypsin Substrate I, Colorimetric、CHYMOTRYPSIN、9004-07-3、4-[[2-[[2-[[1-(4-nitroanilino)-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-4-oxobutanoic acid、a-Chymotrypsin、DTXSID30988741、AKOS024350585、PD166954、FT-0641215、N-Succinyl、α-胰凝乳蛋白酶

产品性质

CAS编号：9004-07-3

EC号：3.4.21.1

MDL号：MFCD00130481

PubChem编号：4052643

酶学委员会编号：3.4.21.1

别名：α-胰凝乳蛋白酶

英文别名：Chymotrypsin Substrate I, Colorimetric|CHYMOTRYPSIN|9004-07-3|4-[[2-[[2-[[1-(4-nitroanilino)-1-oxo-3-phenylpropan-2-yl]amino]-2-oxoethyl]amino]-2-oxoethyl]amino]-4-oxobutanoic acid|a-Chymotrypsin|DTXSID30988741|AKOS024350585|PD166954|FT-0641215|N-Succinyl

规格或纯度：≥45 units/mg protein

英文名称：α-Chymotrypsin from bovine pancreas

单位定义：One Unit hydrolyzes one micromole of benzoyl-L-tyrosine ethyl ester per minute at 25°C, pH 7.8 in the presence of calcium. An activity of 45 units per mg using the above definition, is the equivalent of 10,000 optical density or 1330 N.F. units per mg usi

生化机理：一种丝氨酸蛋白酶，能将与芳香烃或其他大型疏水性侧链（Tyr、Trp、Phe、Met、Leu）结合的肽从键的羧基端水解。 α-Chymotrypsin is a serine peptidase and has 241 amino acid residues contained in three polypeptide chains (A chain-13 residues, B chain-131 residues, and C chain-97 residues) linked by disulfide bridges. Molecular weight of this enzyme is found to be 25 kDa. The pI is 8.75. It selectively hydrolyzes peptide bonds on the C-terminal side of tyrosine, phenylalanine, tryptophan, and leucine. Ca2+ activates and stabilizes the enzyme. The enzyme is inhibited by diisopropyl fluorophosphate (DFP), phenylmethanesulfonyl fluoride (PMSF), N-p-tosyl-L-phenylalanine chloromethyl ketone (TPCK), chymostatin, aprotinin, α1-antitrypsin, and α2-macroglobulin, as well as 10 mM of Cu2+ and Hg2+.

储存温度：2-8°C储存

运输条件：冰袋运输

备注：5g、1g卖完停产，不再备货

产品介绍：Product DescribtionChymotrypsinpreferentiallycatalyzesthehydrolysisofpeptidebondsinvolvingL-isomersoftyrosine,phenylalanineandtryptophan.Italsoreadilyactsuponamidesandestersofsusceptibleaminoacids.Chymotrypsincatalyzesthehydrolysisofbondsofleucyl,methionyl,asparaginylandglutamylresidues.Threetimescrystallizedalphachymotrypsinwhichisanactivationproductofa3Xcrystallizedzymogen.Dialyzedagainst1mMHClandlyophilized.

Isomeric SMILES：C1=CC=C(C=C1)CC(C(=O)NC2=CC=C(C=C2)[N+](=O)[O-])NC(=O)CNC(=O)CNC(=O)CCC(=O)O

WGK Germany：1

RTECS：GC3050000

关联CAS：232-671-2

PubChem CID：4052643

密度：1.047

敏感性：易潮湿

熔点：200℃

象形图：

信号词：Danger

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritationH334 May cause allergy or asthma symptoms or breathing difficulties if inhaled

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P284,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319,P342+P316

个人防护装备：dust mask type N95 (US),Eyeshields,Faceshields,Gloves

产品包装