产品名称

英文名称：Curcumin

同义词

curcumin、458-37-7、Diferuloylmethane、Natural yellow 3、Indian saffron、Kacha haldi、Curcuma、Gelbwurz、Haldar、Curcumin I、Souchet、Haidr、Halad、Halud、Yellow Ginger、Terra Merita、(1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione、Safran d'Inde、Yo-Ki、克扣明、川芎内酯 B

产品性质

CAS编号：458-37-7

分子式：C21H20O6

分子量：368.38

Beilstein号：2306965

EC号：207-280-5

MDL号：MFCD00008365

PubChem编号：969516

别名：克扣明|川芎内酯 B

英文别名：curcumin|458-37-7|Diferuloylmethane|Natural yellow 3|Indian saffron|Kacha haldi|Curcuma|Gelbwurz|Haldar|Curcumin I|Souchet|Haidr|Halad|Halud|Yellow Ginger|Terra Merita|(1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione|Safran d'Inde|Yo-Ki

规格或纯度：分析标准品

英文名称：Curcumin

生化机理：DescriptionIC50 Value N/ACurcumin is a natural phenolic compound with impressive antioxidant properties. Curcumin is recently proved to exert its chemopreventive effects partly throμgh the activation of nuclear factor (erythroid-2 related) factor 2 (Nrf2) [1]. Curcumin possesses chemopreventive properties against several types of cancer, but the molecular mechanisms by which it induces apoptosis of cancer cells and inhibits cancer cell proliferation are not clearly understood.in vitro curcumin induced the expression of forkhead box protein O1 (FOXO1) throμgh activation of extracellular signal-regulated kinase 1/2 signaling. Curcumin inhibited cell proliferation, which was associated with upregulation of the cyclin-dependent kinase inhibitors, p27 and p21, and downregulation of cyclin D1 [2]. Treatment of AGS and HT-29 cells with curcumin enhanced the cleavage of procaspase-3, -7, -8 and -9. Meanwhile, curcumin induced endoplasmic reticulum (ER) str

储存温度：-20°C储存,充氩

运输条件：超低温冰袋运输

产品介绍：易溶于冰乙酸，能溶于醇，不溶于醚带淡绿色荧先，溶于碱呈红棕色，加酸于碱液后变为淡黄色并析出姜黄素沉淀，溶于浓硫酸带黄红色，不溶于水。酸碱指示剂，pH7.8(黄)～9.2(红棕)。显色反应测铍、锆和镁，硼酸盐和试剂。 一种天然酚性物质，抗肿瘤和消炎物质，并具有抗氧化特性，能诱导癌细胞凋亡。

IUPAC Name：(1E,6E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione

INCHI：InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+

InChi Key：VFLDPWHFBUODDF-FCXRPNKRSA-N

Canonical SMILES：COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O

Isomeric SMILES：COC1=C(C=CC(=C1)/C=C/C(=O)CC(=O)/C=C/C2=CC(=C(C=C2)O)OC)O

WGK Germany：3

RTECS：MI5230000

PubChem CID：969516

密度：0.93

敏感性：对空气敏感

熔点：183°C

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritation

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319

产品包装