产品名称

英文名称：DMT-2′O-TBDMS-rA(bz) Phosphoramidite

同义词

Bz-rA Phosphoramidite、104992-55-4、DMT-2'O-TBDMS-Ra(Bz) Phosphoramidite、(2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidi

产品性质

CAS编号：104992-55-4

分子式：C53H66N7O8PSi

分子量：988.19

PubChem编号：11355126

英文别名：Bz-rA Phosphoramidite|104992-55-4|DMT-2'O-TBDMS-Ra(Bz) Phosphoramidite|(2R,3R,4R,5R)-5-(6-Benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-((tert-butyldimethylsilyl)oxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidi

规格或纯度：97%

英文名称：DMT-2′O-TBDMS-rA(bz) Phosphoramidite

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：RNA phosphoramidites, along with RNA CPG, and analogous to DNA synthesis support the synthesis of sequence-specific RNA oligonucleotides for RNA interference (RNAi) and can be used in target validation and other drug development techniques.Modern phosphoramidite-mediated synthesis has enabled routine high-yielding preparations of RNA oligonucleotides. High-quality RNA phosphoramidites are key to low failure rates, the high biological activity of synthesis products, and cost-effectiveness.Key FeaturesIndustry-standard 2′O-TBDMS protective groupConsistent lot-to-lot purity and performanceCompatible with deprotection methods based on methylamine or AMAStandard RNA phosphoramidites provide excellent coupling results whenused with ETT or BTT as an activator; best results are obtained withActivator 42Capping with standard acetic anhydride capping reagent rather than withFast Deprotection Cap AManufactured under a certified ISO 9001 quality systemDMT-2′O-TBDMS-rA(bz) Phosphoramidite is configured for MerMade Synthesizers.

IUPAC Name：N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-[tert-butyl(dimethyl)silyl]oxy-4-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxyoxolan-2-yl]purin-6-yl]benzamide

INCHI：InChI=1S/C53H66N7O8PSi/c1-36(2)60(37(3)4)69(65-32-18-31-54)67-46-44(33-64-53(39-21-16-13-17-22-39,40-23-27-42(62-8)28-24-40)41-25-29-43(63-9)30-26-41)66-51(47(46)68-70(10,11)52(5,6)7)59-35-57-45-48(55-34-56-49(45)59)58-50(61)38-19-14-12-15-20-38/h12-17,19-30,34-37,44,46-47,51H,18,32-33H2,1-11H3,(H,55,56,58,61)/t44-,46-,47-,51-,69?/m1/s1

InChi Key：FFXHNCNNHASXCT-RFMFGJHUSA-N

Canonical SMILES：CC(C)N(C(C)C)P(OCCC#N)OC1C(OC(C1O[Si](C)(C)C(C)(C)C)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC

Isomeric SMILES：CC(C)N(C(C)C)P(OCCC#N)O[C@@H]1[C@H](O[C@H]([C@@H]1O[Si](C)(C)C(C)(C)C)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC

PubChem CID：11355126

产品包装