产品名称

英文名称：7-Amino-4-methyl-3-coumarinylacetic acid(AMCA)

同义词

106562-32-7、2-(7-Amino-4-methyl-2-oxo-2H-chromen-3-yl)acetic acid、7-Amino-4-methylcoumarin-3-acetic acid、7-Amino-4-methyl-3-coumarinylacetic acid、AMCA acid、2-(7-amino-4-methyl-2-oxochromen-3-yl)acetic acid、AMCA-H、2H-1-Benzopyran-3-acetic acid, 7-amino-4-m、7-氨基-4-甲基-3-香豆素醋酸、AMCA-H、2H-1-苯并吡喃-3-乙酸、AMCA酸

产品性质

CAS编号：106562-32-7

分子式：C12H11NO4

分子量：233.22

Beilstein号：7927205

MDL号：MFCD00081051

PubChem编号：129367

别名：7-氨基-4-甲基-3-香豆素醋酸|AMCA-H|2H-1-苯并吡喃-3-乙酸|AMCA酸

英文别名：106562-32-7|2-(7-Amino-4-methyl-2-oxo-2H-chromen-3-yl)acetic acid|7-Amino-4-methylcoumarin-3-acetic acid|7-Amino-4-methyl-3-coumarinylacetic acid|AMCA acid|2-(7-amino-4-methyl-2-oxochromen-3-yl)acetic acid|AMCA-H|2H-1-Benzopyran-3-acetic acid, 7-amino-4-m

规格或纯度：90% (HPLC),用于荧光分析

英文名称：7-Amino-4-methyl-3-coumarinylacetic acid(AMCA)

应用：A blue fluorophore useful for immunofluorescence and peptide labeling.AMCA is a useful agent for labeling proteins. Demonstrates a characteristic absorption peak at 345 nm with a fluorescence emission at 440-460 nm (blue region); however, when conjugated with proteins the absorption peak shifts to 355 nm with a fluorescence emission at 440-460 nm. It has a high fluorescence yield with a sufficient Stokes shift (100 nm) and is relatively photostable.Relatively easy to activate and couple to the N-terminal amino group of a peptide resulting in an acid stable amide bond.

运输条件：常规运输

产品介绍：荧光λex 350 nm，λem 433 nm in methanol Non-activated, Amine-reactive, fluorescent probe that can be conjugated to biomolecules.A blue fluorophore useful for immunofluorescence and peptide labeling.AMCA is a useful agent for labeling proteins. Demonstrates a characteristic absorption peak at 345 nm with a fluorescence emission at 440-460 nm (blue region); however, when conjugated with proteins the absorption peak shifts to 355 nm with a fluorescence emission at 440-460 nm. It has a high fluorescence yield with a sufficient Stokes shift (100 nm) and is relatively photostable.Relatively easy to activate and couple to the N-terminal amino group of a peptide resulting in an acid stable amide bond. Fluorescenceλex 350 nm，λem 433 nm in methanol

IUPAC Name：2-(7-amino-4-methyl-2-oxochromen-3-yl)acetic acid

INCHI：InChI=1S/C12H11NO4/c1-6-8-3-2-7(13)4-10(8)17-12(16)9(6)5-11(14)15/h2-4H,5,13H2,1H3,(H,14,15)

InChi Key：QEQDLKUMPUDNPG-UHFFFAOYSA-N

Canonical SMILES：CC1=C(C(=O)OC2=C1C=CC(=C2)N)CC(=O)O

Isomeric SMILES：CC1=C(C(=O)OC2=C1C=CC(=C2)N)CC(=O)O

WGK Germany：3

PubChem CID：129367

溶解性：Soluble in DMF, DMSO, aqueous base, 10% NaOH solution (freely soluble) at 20 °C, alcohol at 20 °C, acetone at 20 °C, and ether (slightly soluble) at 20 °C. Insoluble in water.

敏感性：对光及湿度敏感

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritation

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319

个人防护装备：dust mask type N95 (US), Eyeshields, Gloves

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