产品名称

英文名称：Pizotifen

同义词

Pizotifen、15574-96-6、PIZOTYLINE、Sandomigran、Litec、Sandomygran、BC-105、Pizotyline [USAN]、Pizotifenum、Pizotifene、Pizotifeno、BC 105、Pizotifan、4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine、Pizotifen [INN]、4-(9,10-Dihydro-、苯噻啶、新度美安

产品性质

CAS编号：15574-96-6

分子式：C19H21NS

分子量：295.44

EC号：239-632-9

MDL号：MFCD00864192

PubChem编号：27400

别名：苯噻啶|新度美安

英文别名：Pizotifen|15574-96-6|PIZOTYLINE|Sandomigran|Litec|Sandomygran|BC-105|Pizotyline [USAN]|Pizotifenum|Pizotifene|Pizotifeno|BC 105|Pizotifan|4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-4-ylidene)-1-methylpiperidine|Pizotifen [INN]|4-(9,10-Dihydro-

规格或纯度：>98.0%(HPLC)

英文名称：Pizotifen

生化机理：Pizotifen is a serotonin antagonist acting mainly at the 5-HT1, 5-HT2A and 5HT2C receptors with some antihistamine activity. It is used for the prevention of vascular headache including migraine and cluster headache.

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：Pizotifen (BC-105) 是 5-HT2 受体的有效拮抗剂，并对 5-HT1C 有高亲和力。Pizotifen (BC-105) is a potent 5-HT2 receptor antagonist, with a high affinity for 5-HT1C binding site. Pizotifen is an antidepresent 5-HT2A receptor antagonist and has the capacity to inhibit serotonin-enhanced ADP-induced platelet aggregation.Pizotifen (BC-105) is a potent 5-HT2 receptor antagonist, with a high affinity for 5-HT1C binding site.

IUPAC Name：1-methyl-4-(6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-2-ylidene)piperidine

INCHI：InChI=1S/C19H21NS/c1-20-11-8-15(9-12-20)19-16-5-3-2-4-14(16)6-7-18-17(19)10-13-21-18/h2-5,10,13H,6-9,11-12H2,1H3

InChi Key：FIADGNVRKBPQEU-UHFFFAOYSA-N

Canonical SMILES：CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1

Isomeric SMILES：CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1

WGK Germany：3

RTECS：TM7165000

关联CAS：15574-96-6

PubChem CID：27400

MeSH Entry Terms：BC 105;BC-105;BC105;Pizotifen;Pizotyline;Polomigran;Sandomigran

Reaxy-Rn：753534

溶解性：DMSO 20 mg/mL (67.70 mM; Need ultrasonic) H2O < 0.1 mg/mL (insoluble)

熔点：149 °C

象形图：

信号词：Warning

危险声明：H302 Harmful if swallowedH361 Suspected of damaging fertility or the unborn child

预防措施声明：P280,P405,P501,P264,P270,P330,P203,P301+P317,P318

Merck Index：7515

产品包装