产品名称

英文名称：AN-2690

同义词

Tavaborole、174671-46-6、5-FLUOROBENZO[C][1,2]OXABOROL-1(3H)-OL、AN-2690、Kerydin、AN2690、2,1-Benzoxaborole, 5-fluoro-1,3-dihydro-1-hydroxy-、AN 2690、5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole、UNII-K124A4EUQ3、5-fluoro-2,1-benzoxaborol-1(3H)-ol、Tavaborole、他伐硼罗、5-氟苯并[c][1,2]氧杂硼戊环-1(3H)-醇

产品性质

CAS编号：174671-46-6

分子式：C7H6BFO2

分子量：151.93

MDL号：MFCD10699483

PubChem编号：11499245

别名：他伐硼罗|5-氟苯并[c][1,2]氧杂硼戊环-1(3H)-醇

英文别名：Tavaborole|174671-46-6|5-FLUOROBENZO[C][1,2]OXABOROL-1(3H)-OL|AN-2690|Kerydin|AN2690|2,1-Benzoxaborole, 5-fluoro-1,3-dihydro-1-hydroxy-|AN 2690|5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole|UNII-K124A4EUQ3|5-fluoro-2,1-benzoxaborol-1(3H)-ol|Tavaborole

规格或纯度：≥98.0%

英文名称：AN-2690

生化机理：AN-2690, a broad-spectrum drμg, is a very promising candidate for treatment of ungual and periungual infections with improved nail penetration and low keratin binding. AN-2690 is an antifungal agent with activity against Trichophyton species. AN-2690 inhibits yeast cytoplasmic leucyl-tRNA synthetase by formation of a stable tRNA(Leu)-AN2690 adduct in the editing site of the enzyme. AN-2690 is currently in clinical trials for onychomycosis topical treatment.

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：5mg、10mg、50mg卖完停产，不再备货

产品介绍：AN-2690(Tavaborole)是抗真菌剂，对发癣菌属有抑制性，对甲癣有潜在应用可能。AN-2690(Tavaborole), an antifungal agent with activity against Trichophyton species, in a topical solution formulation, for the potential treatment of onychomycosis.

PubChem SID：488197556

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488197556

IUPAC Name：5-fluoro-1-hydroxy-3H-2,1-benzoxaborole

INCHI：InChI=1S/C7H6BFO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3,10H,4H2

InChi Key：LFQDNHWZDQTITF-UHFFFAOYSA-N

Canonical SMILES：B1(C2=C(CO1)C=C(C=C2)F)O

Isomeric SMILES：B1(C2=C(CO1)C=C(C=C2)F)O

PubChem CID：11499245

溶解性：10 mM in DMSO；(Soluble) Ethanol

敏感性：吸湿、对热敏感

熔点：132 °C

象形图：

信号词：Danger

危险声明：H315 Causes skin irritationH302 Harmful if swallowedH318 Causes serious eye damageH312 Harmful in contact with skinH332 Harmful if inhaled

预防措施声明：P261,P280,P302+P352,P321,P501,P264,P271,P270,P304+P340,P362+P364,P330,P264+P265,P301+P317,P305+P354+P338,P317,P332+P317

产品包装