产品名称

英文名称：Thioridazine hydrochloride

同义词

Thioridazine hydrochloride、130-61-0、Thioridazine Hcl、Sonapax hydrochloride、Thioridazine chloride、Mellaril hydrochloride、Thioridazine.HCl、Melleril (tablet)、USAF SZ-B、Aldazine、USAF SZ-3、Thioridazine (hydrochloride)、Ridazine、UNII-4WCI67NK8M、EINECS 204-992-8、10-[2-(1-甲基哌啶-2-基)乙基]-2-(甲硫基)-10H-吩噻嗪盐酸盐

产品性质

CAS编号：130-61-0

分子式：C21H27ClN2S2

分子量：407.04

EC号：204-992-8

MDL号：MFCD00012655

PubChem编号：66062

别名：10-[2-(1-甲基哌啶-2-基)乙基]-2-(甲硫基)-10H-吩噻嗪盐酸盐

英文别名：Thioridazine hydrochloride|130-61-0|Thioridazine Hcl|Sonapax hydrochloride|Thioridazine chloride|Mellaril hydrochloride|Thioridazine.HCl|Melleril (tablet)|USAF SZ-B|Aldazine|USAF SZ-3|Thioridazine (hydrochloride)|Ridazine|UNII-4WCI67NK8M|EINECS 204-992-8|

规格或纯度：98%

英文名称：Thioridazine hydrochloride

生化机理：多巴胺受体拮抗剂（K i值为16（D 2），10（D 1），7.8（D 3）和31（D 4）nM）。还抑制CYP2D6（IC 50 = 2.7μM）。抗精神病药。显示抗结核/耐药结核的特性。

储存温度：避光,室温

运输条件：常规运输

备注：25g,卖完停产，不再备货.如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Thioridazine hydrochloride has been used as an intercalating agent for analyzing the integrity of double-stranded DNA (dsDNA) using square-wave voltammetry (SWV) techniques. Thioridazine hydrochloride has also been used as a positive control for the inhibition of hepatic enzyme cytochrome P4502D6 (CYP2D6) in human liver microsomes.Thioridazine hydrochloride has been used as an intercalating agent for analyzing the integrity of double-stranded DNA (dsDNA) using square-wave voltammetry (SWV) techniques. Thioridazine hydrochloride has also been used as a positive control for the inhibition of hepatic enzyme cytochrome P4502D6 (CYP2D6) in human liver microsomes.

IUPAC Name：10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfanylphenothiazine;hydrochloride

INCHI：InChI=1S/C21H26N2S2.ClH/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23;/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3;1H

InChi Key：NZFNXWQNBYZDAQ-UHFFFAOYSA-N

Canonical SMILES：CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)SC.Cl

Isomeric SMILES：CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)SC.Cl

WGK Germany：3

RTECS：SP2275000

关联CAS：50-52-2

PubChem CID：66062

溶解性：Soluble in water (75 mM), DMSO (100 mM), chloroform, ethanol, and methanol.

敏感性：对光线、湿度敏感

熔点：161-163℃

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritationH302 Harmful if swallowedH400 Very toxic to aquatic lifeH410 Very toxic to aquatic life with long lasting effects

预防措施声明：P261,P305+P351+P338,P273,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P403+P233,P362+P364,P391,P330,P264+P265,P301+P317,P337+P317,P332+P317,P319

Merck Index：9359

个人防护装备：dust mask type N95 (US)， Eyeshields， Gloves

产品包装