产品名称

英文名称：cholest-5-ene-3β,25-diol-d6

同义词

26,26,26,27,27,27-六氢胆甾醇-5-烯-3β,25-二醇、25-羟基胆碱-5-en-3-醇(d6)、25-羟基胆固醇-d6

产品性质

CAS编号：88247-69-2

分子式：C27H40D6O2

分子量：408.69

PubChem编号：42608393

别名：26,26,26,27,27,27-六氢胆甾醇-5-烯-3β,25-二醇|25-羟基胆碱-5-en-3-醇(d6)|25-羟基胆固醇-d6

规格或纯度：99 atom % D

英文名称：cholest-5-ene-3β,25-diol-d6

生化机理：25-hydroxycholesterol is a liver X receptor ligand. This bioactive lipid regulates immune response and macrophages production from monocytes. 25-HC serves as an antiviral effector and may have therapeutic potential. It reduces cholesterol biosynthesis by inactivating sterol regulatory element binding protein and inhibits HMG-CoA reductase (HMGCR). 25-HC may play a protective role in myocardial ischemia-reperfusion injury by inhibiting apoptosis and regulating mitogen-activated protein kinase (MAPK) pathway.

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：application25-hydroxycholesterol-d6 has been used as an internal standardin the quantification of 25-OHC in jejunum samples by liquid chromatography with tandem mass spectrometry (LC-MS-MS)in plasma samples by liquid chromatography-mass spectrometry analysisfor calibration curve generation for plasma oxysterol quantification

IUPAC Name：(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-7,7,7-trideuterio-6-hydroxy-6-(trideuteriomethyl)heptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

INCHI：InChI=1S/C27H46O2/c1-18(7-6-14-25(2,3)29)22-10-11-23-21-9-8-19-17-20(28)12-15-26(19,4)24(21)13-16-27(22,23)5/h8,18,20-24,28-29H,6-7,9-17H2,1-5H3/t18-,20+,21+,22-,23+,24+,26+,27-/m1/s1/i2D3,3D3

InChi Key：INBGSXNNRGWLJU-KHKDDIDZSA-N

Canonical SMILES：CC(CCCC(C)(C)O)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C

Isomeric SMILES：[2H]C([2H])([2H])C(CCC[C@@H](C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C)(C([2H])([2H])[2H])O

关联CAS：2140-46-7（unlabelled）

PubChem CID：42608393

溶解性：Chloroform (Slightly), DMSO (Slightly)

熔点：>155°C (dec.)

产品包装