产品名称

英文名称：Saxagliptin hydrochloride

同义词

Saxagliptin hydrochloride、709031-78-7、Saxagliptin HCl、Onglyza、UNII-Z8J84YIX6L、Z8J84YIX6L、(1S,3S,5S)-2-((2S)-2-Amino-2-(3-hydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride、Saxagliptin (hydrochloride)、(1S,3S,5S)-2-[(2S)-2-、沙克列汀盐酸盐

产品性质

CAS编号：709031-78-7

分子式：C18H26ClN3O2

分子量：351.871

PubChem编号：49800073

别名：沙克列汀盐酸盐

英文别名：Saxagliptin hydrochloride|709031-78-7|Saxagliptin HCl|Onglyza|UNII-Z8J84YIX6L|Z8J84YIX6L|(1S,3S,5S)-2-((2S)-2-Amino-2-(3-hydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride|Saxagliptin (hydrochloride)|(1S,3S,5S)-2-[(2S)-2-

规格或纯度：97%

英文名称：Saxagliptin hydrochloride

生化机理：高亲和力DPP-IV抑制剂（Ki = 0.6 nM）。抑制血浆DPP-IV（87％）。可以提高Zuckerfa /地区的葡萄糖清除率。

储存温度：2-8°C储存

运输条件：冰袋运输

IUPAC Name：(1S,3S,5S)-2-[(2S)-2-amino-2-(3-hydroxy-1-adamantyl)acetyl]-2-azabicyclo[3.1.0]hexane-3-carbonitrile;hydrochloride

INCHI：InChI=1S/C18H25N3O2.ClH/c19-8-13-2-12-3-14(12)21(13)16(22)15(20)17-4-10-1-11(5-17)7-18(23,6-10)9-17;/h10-15,23H,1-7,9,20H2;1H/t10?,11?,12-,13+,14+,15-,17?,18?;/m1./s1

InChi Key：TUAZNHHHYVBVBR-NHKADLRUSA-N

Canonical SMILES：C1C2CC2N(C1C#N)C(=O)C(C34CC5CC(C3)CC(C5)(C4)O)N.Cl

Isomeric SMILES：C1[C@@H]2C[C@@H]2N([C@@H]1C#N)C(=O)[C@H](C34CC5CC(C3)CC(C5)(C4)O)N.Cl

PubChem CID：49800073

溶解性：溶于water, 最高浓度 (mg/mL) 35.19, 最高浓度(mM) 100；溶于DMSO, 最高浓度 (mg/mL) 35.19, 最高浓度(mM) 100

象形图：

信号词：Danger

危险声明：H335 May cause respiratory irritationH351 Suspected of causing cancerH317 May cause an allergic skin reactionH372 Causes damage to organs through prolonged or repeated exposureH361 Suspected of damaging fertility or the unborn child

预防措施声明：P261,P280,P302+P352,P321,P405,P501,P264,P260,P271,P270,P304+P340,P403+P233,P272,P333+P313,P362+P364,P203,P318,P319

产品包装