产品名称

英文名称：AGI-6780

同义词

AGI-6780、1432660-47-3、AGI6780、N-cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoromethyl)phenyl)ureido)benzenesulfonamide、AGI 6780、1-[5-(Cyclopropylsulfamoyl)-2-Thiophen-3-Yl-Phenyl]-3-[3-(Trifluoromethyl)phenyl]urea、1-[5-(CYCLOPROPYLSULFAMOYL)-2-(THIOPHEN-

产品性质

CAS编号：1432660-47-3

分子式：C21H18F3N3O3S2

分子量：481.51

PubChem编号：71299339

英文别名：AGI-6780|1432660-47-3|AGI6780|N-cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoromethyl)phenyl)ureido)benzenesulfonamide|AGI 6780|1-[5-(Cyclopropylsulfamoyl)-2-Thiophen-3-Yl-Phenyl]-3-[3-(Trifluoromethyl)phenyl]urea|1-[5-(CYCLOPROPYLSULFAMOYL)-2-(THIOPHEN-

规格或纯度：≥98%

英文名称：AGI-6780

生化机理：AGI-6780是第一个高效异柠檬酸脱氢酶（IDH）选择性抑制剂，能与突变型IDH2-R140Q的二聚体变构结合，IC50为23 nM。

储存温度：2-8°C储存

运输条件：冰袋运输

备注：卖完停产，不再备货

产品介绍：AGI-6780 是一种强效的选择性IDH2 R140Q mutant抑制剂，其IC50为23 nM。AGI-6780 is a potent and selective inhibitor of IDH2 R140Q mutant with IC50 of 23 nM.

IUPAC Name：1-[5-(cyclopropylsulfamoyl)-2-thiophen-3-ylphenyl]-3-[3-(trifluoromethyl)phenyl]urea

INCHI：InChI=1S/C21H18F3N3O3S2/c22-21(23,24)14-2-1-3-16(10-14)25-20(28)26-19-11-17(32(29,30)27-15-4-5-15)6-7-18(19)13-8-9-31-12-13/h1-3,6-12,15,27H,4-5H2,(H2,25,26,28)

InChi Key：CCAWRGNYALGPQH-UHFFFAOYSA-N

Canonical SMILES：C1CC1NS(=O)(=O)C2=CC(=C(C=C2)C3=CSC=C3)NC(=O)NC4=CC=CC(=C4)C(F)(F)F

Isomeric SMILES：C1CC1NS(=O)(=O)C2=CC(=C(C=C2)C3=CSC=C3)NC(=O)NC4=CC=CC(=C4)C(F)(F)F

WGK Germany：3

PubChem CID：71299339

溶解性：25°C DMSO

产品包装