产品名称

英文名称：RKI-1447

同义词

RKI-1447、1342278-01-6、1-(3-hydroxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea、RKI1447、1-[(3-Hydroxyphenyl)methyl]-3-(4-Pyridin-4-Yl-1,3-Thiazol-2-Yl)urea、F8GZ6C9MKZ、1-[(3-hydroxyphenyl)methyl]-3-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]urea、RKI 1447、N-((3-Hydr

产品性质

CAS编号：1342278-01-6

分子式：C16H14N4O2S

分子量：326.37

PubChem编号：60138149

英文别名：RKI-1447|1342278-01-6|1-(3-hydroxybenzyl)-3-(4-(pyridin-4-yl)thiazol-2-yl)urea|RKI1447|1-[(3-Hydroxyphenyl)methyl]-3-(4-Pyridin-4-Yl-1,3-Thiazol-2-Yl)urea|F8GZ6C9MKZ|1-[(3-hydroxyphenyl)methyl]-3-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]urea|RKI 1447|N-((3-Hydr

规格或纯度：≥98%

英文名称：RKI-1447

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：卖完停产，不再备货

产品介绍：RKI-1447是一种有效的ROCK1和ROCK2抑制剂，IC50分别为14.5 nM和6.2 nM，有抗侵入和抗肿瘤活性。RKI-1447 is a potent inhibitor of ROCK1 and ROCK2, with IC50 of 14.5 nM and 6.2 nM, respectively, has anti-invasive and antitumor activities.

IUPAC Name：1-[(3-hydroxyphenyl)methyl]-3-(4-pyridin-4-yl-1,3-thiazol-2-yl)urea

INCHI：InChI=1S/C16H14N4O2S/c21-13-3-1-2-11(8-13)9-18-15(22)20-16-19-14(10-23-16)12-4-6-17-7-5-12/h1-8,10,21H,9H2,(H2,18,19,20,22)

InChi Key：GDVRVPIXWXOKQO-UHFFFAOYSA-N

Canonical SMILES：C1=CC(=CC(=C1)O)CNC(=O)NC2=NC(=CS2)C3=CC=NC=C3

Isomeric SMILES：C1=CC(=CC(=C1)O)CNC(=O)NC2=NC(=CS2)C3=CC=NC=C3

PubChem CID：60138149

ChEMBL Ligand：CHEMBL3218011

CAS Registry No.：1342278-01-6

RCSB PDB Ligand：07R

溶解性：25°C DMSO 65 mg/mL; Water <1 mg/mL; EtOH <1 mg/mL

产品包装