产品名称

英文名称：4-Chloro-L-phenylalanine

同义词

L-PCPA 、 (S)-4-CHLOROPHENYLALANINE 、 4-Chloro-3-phenyl-L-alanine 、 PD132687 、 SNM151OE2C 、 DTXSID10161813 、 L-Phenylalanine, 4-chloro- 、 (2S)-2-amino-3-(4-chlorophenyl)propionic acid 、 AKOS010367583 、 L-PHE(4-CL)-OH 、 Q27120767 、 (2S)-2-azanyl-3-(4-chloro、L-4-氯苯丙氨酸

产品性质

CAS编号：14173-39-8

分子式：C9H10ClNO2

分子量：199.63

Beilstein号：2416150

EC号：238-023-5

MDL号：MFCD00063065

PubChem编号：736190

别名：L-4-氯苯丙氨酸

英文别名：L-PCPA | (S)-4-CHLOROPHENYLALANINE | 4-Chloro-3-phenyl-L-alanine | PD132687 | SNM151OE2C | DTXSID10161813 | L-Phenylalanine, 4-chloro- | (2S)-2-amino-3-(4-chlorophenyl)propionic acid | AKOS010367583 | L-PHE(4-CL)-OH | Q27120767 | (2S)-2-azanyl-3-(4-chloro

规格或纯度：98%

英文名称：4-Chloro-L-phenylalanine

生化机理：4-Chloro-L-phenylalanine (L-PCPA) inhibits the synthesis of 5-hydroxytryptamine (5-HT). 4-Chloro-DL-phenylalanine (PCPA) depletes the serotonin levels in the brain by its inhibitory effect on tryptophan hydroxylase (Tph). Studies support the protective effects of PCPA against monocrotaline-induced pulmonary vascular remodeling as well as in lung inflammation.

储存温度：-20°C储存,充氩

运输条件：超低温冰袋运输

产品介绍：色氨酸羟化酶（Tryptophan hydroxylase）抑制剂Application4-Chloro-L-phenylalanine (L-PCPA) has been usedto block serotonin synthesis by inhibiting tryptophan hydroxylase (TPH)to study its behavioral and electrographic effects on epileptic senegalese baboon (Papiopapio)as a substrate for Chromobacteriumviolaceum phenylalanine hydroxylaseto incubate sea urchin embryos for immunohistochemistry

IUPAC Name：(2S)-2-amino-3-(4-chlorophenyl)propanoic acid

INCHI：InChI=1S/C9H10ClNO2/c10-7-3-1-6(2-4-7)5-8(11)9(12)13/h1-4,8H,5,11H2,(H,12,13)/t8-/m0/s1

InChi Key：NIGWMJHCCYYCSF-QMMMGPOBSA-N

Canonical SMILES：C1=CC(=CC=C1CC(C(=O)O)N)Cl

Isomeric SMILES：C1=CC(=CC=C1C[C@@H](C(=O)O)N)Cl

WGK Germany：3

PubChem CID：736190

UN Number：2811

溶解性：Soluble in acetic acid. Slightly soluble in water.

密度：1.336

敏感性：对空气敏感

熔点：235-238°C

象形图：

信号词：Danger

危险声明：H301 Toxic if swallowedH317 May cause an allergic skin reaction

预防措施声明：P261,P280,P302+P352,P321,P405,P501,P264,P270,P272,P333+P313,P362+P364,P330,P301+P316

个人防护装备：Eyeshields,Faceshields,Gloves,type P2 (EN 143) respirator cartridges

产品包装