产品名称

英文名称：Streptomycin sulfate

同义词

STREP SOL 、 STREPTOMYCIN SULFATE [GREEN BOOK] 、 D-STREPTAMINE, O-2-DEOXY-2-(METHYLAMINO)-alpha-L-GLUCOPYRANOSYL-(1->2)-O-5-DEOXY-3-C-FORMYL-alpha-L-LYXOFURANOSYL-(1->4)-N,N'-BIS(AMINOIMINOMETHYL)-, SULPHATE (23) (SALT) 、 Streptomycin A sulfate 、 CCRIS 5、硫酸链霉素 、 链霉素硫酸盐 、 链霉素

产品性质

CAS编号：3810-74-0

分子式：C42H84N14O36S3

分子量：1457.38

Beilstein号：3894995

EC号：223-286-0

MDL号：MFCD00037023

PubChem编号：19648

别名：硫酸链霉素 | 链霉素硫酸盐 | 链霉素

英文别名：STREP SOL | STREPTOMYCIN SULFATE [GREEN BOOK] | D-STREPTAMINE, O-2-DEOXY-2-(METHYLAMINO)-alpha-L-GLUCOPYRANOSYL-(1->2)-O-5-DEOXY-3-C-FORMYL-alpha-L-LYXOFURANOSYL-(1->4)-N,N'-BIS(AMINOIMINOMETHYL)-, SULPHATE (23) (SALT) | Streptomycin A sulfate | CCRIS 5

规格或纯度：720 I.U./mg

英文名称：Streptomycin sulfate

生化机理：Mode of Action Inhibits prokaryote protein synthesis. Binds to S12 protein of 30S ribosomal subunit, preventing the transition from initiation complex to chain-elongating ribosome, causing miscoding or inhibiting initiation. Mode of Resistance Mutation in rpsL (gene for S12 ribosomal protein) prevents binding of streptomycin to ribosome. Aminoglycoside phosphotransferase also inactivates. Antimicrobial spectrum Gram-negative and Gram-positive bacteria.

储存温度：2-8°C储存

运输条件：冰袋运输

产品介绍：Streptomycin sulfate is an aminocyclitol glycoside antibiotic which interferes with protein synthesis in prokaryotes. This antibiotic is effective against both gram-positive and gram-negative bacteria and is frequently used in cell culture media. Streptomycin inhibits protein synthesis by binding to the 30S ribosomal subunit at the S12 protein thereby inducing a misreading of the genetic code, inhibiting the initiation of translation of DNA which then results in death for a susceptible bacterium.An antibiotic for cell culture.Streptomycin sulfate is an aminocyclitol glycoside antibiotic which interferes with protein synthesis in prokaryotes. This antibiotic is effective against both gram-positive and gram-negative bacteria and is frequently used in cell culture media. Streptomycin inhibits protein synthesis by binding to the 30S ribosomal subunit at the S12 protein thereby inducing a misreading of the genetic code, inhibiting the initiation of translation of DNA which then results in death for a susceptible bacterium.An antibiotic for cell culture.

PubChem SID：488182553

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488182553

IUPAC Name：2-[(1R,2R,3S,4R,5R,6S)-3-(diaminomethylideneamino)-4-[(2R,3R,4R,5S)-3-[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine;sulfuric acid

INCHI：InChI=1S/2C21H39N7O12.3H2O4S/c2*1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;3*1-5(2,3)4/h2*4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28);3*(H2,1,2,3,4)/t2*5-,6-,7+,8-,9-,10-,11+,12-,13-,14+,15+,16-,17-,18-,21+;;;/m00.../s1

InChi Key：QTENRWWVYAAPBI-YCRXJPFRSA-N

Canonical SMILES：CC1C(C(C(O1)OC2C(C(C(C(C2O)O)N=C(N)N)O)N=C(N)N)OC3C(C(C(C(O3)CO)O)O)NC)(C=O)O.CC1C(C(C(O1)OC2C(C(C(C(C2O)O)N=C(N)N)O)N=C(N)N)OC3C(C(C(C(O3)CO)O)O)NC)(C=O)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O

Isomeric SMILES：C[C@H]1[C@@]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H]([C@@H]([C@H]2O)O)N=C(N)N)O)N=C(N)N)O[C@H]3[C@H]([C@@H]([C@H]([C@@H](O3)CO)O)O)NC)(C=O)O.C[C@H]1[C@@]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H]([C@@H]([C@H]2O)O)N=C(N)N)O)N=C(N)N)O[C@H]3[C@H]([C@@H]([C@H]([C@@H](O3)CO)O)O)NC)(C=O)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O

WGK Germany：3

RTECS：WK4990000

关联CAS：57-92-1

PubChem CID：19648

溶解性：Soluble in water (50 mg/ml).

密度：0.873

比旋光度：-85° (C=1,H2O)

熔点：250 °C

象形图：

信号词：Danger

危险声明：H319 Causes serious eye irritationH335 May cause respiratory irritationH302 Harmful if swallowedH317 May cause an allergic skin reactionH400 Very toxic to aquatic lifeH410 Very toxic to aquatic life with long lasting effectsH372 Causes damage to organs through prolonged or repeated exposureH360 May damage fertility or the unborn childH361 Suspected of damaging fertility or the unborn child

预防措施声明：P261,P305+P351+P338,P273,P280,P302+P352,P321,P405,P501,P264,P260,P271,P270,P304+P340,P403+P233,P272,P333+P313,P362+P364,P391,P330,P203,P264+P265,P301+P317,P318,P337+P317,P319

Merck Index：8826

个人防护装备：dust mask type N95 (US),Eyeshields,Faceshields,Gloves

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