产品名称

英文名称：tert-Butyl P,P-dimethylphosphonoacetate

同义词

62327-21-3、tert-Butyl 2-(dimethoxyphosphoryl)acetate、tert-Butyl P,P-dimethylphosphonoacetate、tert-Butyl O,O-dimethylphosphonoacetate、Tert-butyl 2-dimethoxyphosphorylacetate、tert-butyl dimethylphosphonoacetate、MFCD00042939、dimethylphosphonoacetic acid tert、(叔丁氧羰基)甲基膦酸二甲酯

产品性质

CAS编号：62327-21-3

分子式：(CH3O)2P(O)CH2COOC(CH3)3

分子量：224.19

Beilstein号：4861886

MDL号：MFCD00042939

PubChem编号：4564495

别名：(叔丁氧羰基)甲基膦酸二甲酯

英文别名：62327-21-3|tert-Butyl 2-(dimethoxyphosphoryl)acetate|tert-Butyl P,P-dimethylphosphonoacetate|tert-Butyl O,O-dimethylphosphonoacetate|Tert-butyl 2-dimethoxyphosphorylacetate|tert-butyl dimethylphosphonoacetate|MFCD00042939|dimethylphosphonoacetic acid tert

规格或纯度：≥97.0% (GC)

英文名称：tert-Butyl P,P-dimethylphosphonoacetate

运输条件：常规运输

产品介绍：Horner-Wittig 试剂，优先生成 (E)-α,β-不饱和酯，这种酯可与酸发生轻度皂化反应。也可用于通过还原烷基化反应合成衍生物Reactant for ·Preparation of phosphonate terminated PPH dendrimers as anti-HIV-1 agents ·Preparation of monodehydro diketopiperazines from ketoacyl amino acid amides via acid-catalyzed cyclization ·Preparation of α,β-unsaturated esters for use in the guanidine-catalyzed oxa-Michael addition ·Preparation of myxopyronin B and desmethyl myxopyronin B analogs, with antibacterial activity and inhibitory activity against bacterial RNA polymerase ·Allylation and subsequent ring-closing metathesis in presence of Grubbs′ catalyst or intramolecular rhodium-catalyzed cyclopropanation reactionsHorner-Wittig reagent giving preferentially (E)-α,β-unsat. esters which are mildly saponified with acid. Synthesis of derivatives by reductive alkylationReactant for ·Preparation of phosphonate terminated PPH dendrimers as anti-HIV-1 agents ·Preparation of monodehydro diketopiperazines from ketoacyl amino acid amides via acid-catalyzed cyclization ·Preparation of α,β-unsaturated esters for use in the guanidine-catalyzed oxa-Michael addition ·Preparation of myxopyronin B and desmethyl myxopyronin B analogs, with antibacterial activity and inhibitory activity against bacterial RNA polymerase ·Allylation and subsequent ring-closing metathesis in presence of Grubbs′ catalyst or intramolecular rhodium-catalyzed cyclopropanation reactions

IUPAC Name：tert-butyl 2-dimethoxyphosphorylacetate

INCHI：InChI=1S/C8H17O5P/c1-8(2,3)13-7(9)6-14(10,11-4)12-5/h6H2,1-5H3

InChi Key：SAZYDWOWLRDDRQ-UHFFFAOYSA-N

Canonical SMILES：CC(C)(C)OC(=O)CP(=O)(OC)OC

Isomeric SMILES：CC(C)(C)OC(=O)CP(=O)(OC)OC

WGK Germany：3

PubChem CID：4564495

密度：1.131

折光率：1.434

闪点(℉)：230 °F

闪点(℃)：110 °C

沸点：86-87 °C/0.02 mmHg(lit.)

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritation

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319

个人防护装备：Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter

产品包装