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产品详情
产品名称 英文名称:Coenzyme A (lithium salt hydrate) 同义词 Coenzyme A (lithium salt) 、 CoA、辅酶 A 锂盐 产品性质 CAS编号:18439-24-2 分子式:C21H33N7O16P3S • XLi [XH2O] 分子量:764.5(free basis) MDL号:MFCD00075848 PubChem编号:16219106 别名:辅酶 A 锂盐 英文别名:Coenzyme A (lithium salt) | CoA 规格或纯度:>95% 英文名称:Coenzyme A (lithium salt hydrate) 储存温度:-20°C储存,充氩 运输条件:超低温冰袋运输 产品介绍:Product DescriptionCoenzyme A (CoA) is synthesized from phosphopantothenate by the action of enzyme pantothenate kinase and is the master regulator. Product ApplicationCoenzyme A trilithium salt has been used in standard curve generation in the kinetic assay of acetyltransferase Gcn5 acylation as a cofactor in JNADH and JNADPH production assay in the labeling of Alexa647 (AF647) probeBiochemical and physiological mechanismsCoenzyme A (CoA, CoASH, HSCoA) is a coenzyme that facilitates enzymatic acyl-group transfer reactions and supports the synthesis and oxidation of fatty acids. CoA is involved in the mechanisms of a wide variety of enzymes. Acyl CoA accumulation is implicated in metabolic disorders and may indirectly lead to the pathogenesis associated with carbon-induced mitochondrial stress heart failure, diabetes and obesity. IUPAC Name:trilithium;[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-hydroxy-2-[[[[3-hydroxy-2,2-dimethyl-4-oxo-4-[[3-oxo-3-(2-sulfanylethylamino)propyl]amino]butoxy]-oxidophosphoryl]oxy-oxidophosphoryl]oxymethyl]oxolan-3-yl] hydrogen phosphate INCHI:InChI=1S/C21H36N7O16P3S.3Li/c1-21(2,16(31)19(32)24-4-3-12(29)23-5-6-48)8-41-47(38,39)44-46(36,37)40-7-11-15(43-45(33,34)35)14(30)20(42-11)28-10-27-13-17(22)25-9-26-18(13)28;;;/h9-11,14-16,20,30-31,48H,3-8H2,1-2H3,(H,23,29)(H,24,32)(H,36,37)(H,38,39)(H2,22,25,26)(H2,33,34,35);;;/q;3*+1/p-3/t11-,14-,15-,16?,20-;;;/m1.../s1 InChi Key:QSCBPHBAFBVXRK-HJKJOZROSA-K Canonical SMILES:[Li+].[Li+].[Li+].CC(C)(COP(=O)([O-])OP(=O)([O-])OCC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)[O-])C(C(=O)NCCC(=O)NCCS)O Isomeric SMILES:[Li+].[Li+].[Li+].CC(C)(COP(=O)([O-])OP(=O)([O-])OC[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)[O-])C(C(=O)NCCC(=O)NCCS)O PubChem CID:16219106 溶解性:DMSO (Slightly, Heated), Water (Slightly) 敏感性:对湿度敏感 象形图: 信号词:Warning 危险声明:H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritation 预防措施声明:P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319 产品包装
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