产品名称

英文名称：1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil

同义词

FIALURIDINE、69123-98-4、FIAU、Fluoroiodoarauridine、1-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)-5-iodouracil、1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione、53T7IN77LC、1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxym、FIAU、非阿尿苷、2'-氟-5-碘尿嘧啶

产品性质

CAS编号：69123-98-4

分子式：C9H10FIN2O5

分子量：372.09

MDL号：MFCD00866922

PubChem编号：50313

别名：FIAU|非阿尿苷|2'-氟-5-碘尿嘧啶

英文别名：FIALURIDINE|69123-98-4|FIAU|Fluoroiodoarauridine|1-(2-Deoxy-2-fluoro-b-D-arabinofuranosyl)-5-iodouracil|1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione|53T7IN77LC|1-((2R,3S,4R,5R)-3-Fluoro-4-hydroxy-5-(hydroxym

规格或纯度：98%

英文名称：1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil

生化机理：Fialuridine (1-(2-deoxy-2-fluoro-β-d-arabinofuranosyl)-5-iodouracil, or FIAU) and its metabolites blocks DNA polymerase at sites of multiple adjacent analog incorporation, reduces the presence of mtDNA (mitochondrial DNA) and results in mitochondrial structural defects in cultured hepatoblasts. It is considered as an efficient drug against hepatitis B virus (HBV) infection. Fialuridine is a nucleoside analog antiviral agent. The compound displays significant mitochondrial toxicity.

储存温度：避光,-20°C储存

运输条件：超低温冰袋运输

产品介绍：产品介绍Fialuridine 是一种具有抗病毒活性的核苷类似物。Fialuridine 具有抗正痘病毒活性。Product descriptionFialuridine is a nucleoside analog with antiviral activity. Fialuridine shows anti-orthopoxvirus activity.ApplicationFialuridine has been used in the selection of clones.

IUPAC Name：1-[(2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-iodopyrimidine-2,4-dione

INCHI：InChI=1S/C9H10FIN2O5/c10-5-6(15)4(2-14)18-8(5)13-1-3(11)7(16)12-9(13)17/h1,4-6,8,14-15H,2H2,(H,12,16,17)/t4-,5+,6-,8-/m1/s1

InChi Key：IPVFGAYTKQKGBM-BYPJNBLXSA-N

Canonical SMILES：C1=C(C(=O)NC(=O)N1C2C(C(C(O2)CO)O)F)I

Isomeric SMILES：C1=C(C(=O)NC(=O)N1[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)F)I

WGK Germany：3

RTECS：YQ9512500

PubChem CID：50313

Reaxy-Rn：892318

敏感性：对热敏感；对光线敏感

熔点：226°C

象形图：

信号词：Danger

危险声明：H301 Toxic if swallowedH312 Harmful in contact with skinH332 Harmful if inhaled

预防措施声明：P261,P280,P302+P352,P321,P405,P501,P264,P271,P270,P304+P340,P362+P364,P330,P301+P316,P317

Merck Index：4069

产品包装