产品名称

英文名称：Levosulpiride

同义词

Levopraid (TN)、Levosulpiridum、BCP9000853、NCGC00024853-01、LEVOSULPIRIDE [MART.]、NCGC00024853-09、SMR000466366、JTG7R315LK、Levosulpiride、NCGC00024853-06、NC00097、S-(-)-N-(1-Ethyl-2-pyrrolidinomethyl)-2-methoxy-5-sulfamoylebenzamide、LEVOSULPIRIDE [WHO-DD]、HMS22、左旋舒必利

产品性质

CAS编号：23672-07-3

分子式：C15H23N3O4S

分子量：341.43

MDL号：MFCD00055220

PubChem编号：688272

别名：左旋舒必利

英文别名：Levopraid (TN)|Levosulpiridum|BCP9000853|NCGC00024853-01|LEVOSULPIRIDE [MART.]|NCGC00024853-09|SMR000466366|JTG7R315LK|Levosulpiride|NCGC00024853-06|NC00097|S-(-)-N-(1-Ethyl-2-pyrrolidinomethyl)-2-methoxy-5-sulfamoylebenzamide|LEVOSULPIRIDE [WHO-DD]|HMS22

规格或纯度：≥98%

英文名称：Levosulpiride

生化机理：It is a D2DR(D2 dopamine receptor) and D3DR(D3 dopamine receptor) inhibitor.Selective D 2 -like dopamine antagonist (K i values are ~ 0.015, ~ 0.013, and 1 μM at D 2 , D 3 , and D 4 receptors, respectively). Active enantiomer of Sulpiride. Antipsychotic and prokinetic agent.

应用：It was used to study the effect of dopamine D2 receptor function on activation of KCNQ potassium channels and on depression-like behavior in ovariectomized female rats.

储存温度：2-8°C储存

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：It was used to study the effect of dopamine D2 receptor function on activation of KCNQ potassium channels and on depression-like behavior in ovariectomized female rats.It was used to study the effect of dopamine D2 receptor function on activation of KCNQ potassium channels and on depression-like behavior in ovariectomized female rats.

ALogP：0.6

IUPAC Name：N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-methoxy-5-sulfamoylbenzamide

INCHI：InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1

InChi Key：BGRJTUBHPOOWDU-NSHDSACASA-N

Canonical SMILES：CCN1CCCC1CNC(=O)C2=C(C=CC(=C2)S(=O)(=O)N)OC

Isomeric SMILES：CCN1CCC[C@H]1CNC(=O)C2=C(C=CC(=C2)S(=O)(=O)N)OC

PubChem CID：688272

DrugBank Ligand：DB00391

CAS Registry No.：23672-07-3

ChEBI：CHEBI64119

ChEMBL Ligand：CHEMBL267044

BindingDB Ligand：81774

Wikipedia：Sulpiride

DrugCentral Ligand：1577

GPCRdb Ligand：(-)-sulpiride

溶解性：Soluble in water (partly), DMF, DMSO (69 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), and ethanol (10 mM).

敏感性：对热敏感

比旋光度：-69° (C=3,DMF)

熔点：183-186°C

Merck Index：8989

产品包装