产品名称

英文名称：Dihydrofolic acid

同义词

Dihydrofolic acid、dihydrofolate、4033-27-6、7,8-Dihydrofolic acid、7,8-Dihydropteroyl-L-glutamic acid、7,8-dihydrofolate、7,8-Dihydropteroylglutamate、7,8-Dihydro-L-folic acid、CHEBI15633、KXP0KNM559、CHEMBL46294、(2S)-2-[[4-[(2-amino-4-oxo-7,8-dihydro-1H-pteridin、FAH2、二氢蝶酰- L -谷氨酸、7,8-二氢蝶酰- L -谷氨酸

产品性质

CAS编号：4033-27-6

分子式：C19H21N7O6

分子量：443.41

Beilstein号：69017

MDL号：MFCD00083619

PubChem编号：135398604

别名：FAH2|二氢蝶酰- L -谷氨酸|7,8-二氢蝶酰- L -谷氨酸

英文别名：Dihydrofolic acid|dihydrofolate|4033-27-6|7,8-Dihydrofolic acid|7,8-Dihydropteroyl-L-glutamic acid|7,8-dihydrofolate|7,8-Dihydropteroylglutamate|7,8-Dihydro-L-folic acid|CHEBI15633|KXP0KNM559|CHEMBL46294|(2S)-2-[[4-[(2-amino-4-oxo-7,8-dihydro-1H-pteridin

规格或纯度：90%

英文名称：Dihydrofolic acid

生化机理：Folic acid (FA) and dihydrofolic acid (FAH2) are substrates of dihydrofolate reductase(s) which reduce them to tetrahydrofolate (THF), which in turn supports ‘one carbon’ transfer. Tetrahydrofolates are required for de novo synthesis of purines, thymidylic acid and various amino acids and for post-translational methylation (epigenetics).

储存温度：避光,-20°C储存

运输条件：超低温冰袋运输

备注：100mg卖完停产，不再备货

产品介绍：Intermediate in mammalian conversion of dietary folic acid to tetrahydrofolate by dihydrofolate reductase (DHFR). In bacteria, dihydrofolic acid is generated from 7,8-dihydropteroate by dihydrofolate synthetase.DescriptionIntermediate in mammalian conversion of dietary folic acid to tetrahydrofolate by dihydrofolate reductase (DHFR). In bacteria, dihydrofolic acid is generated from 7,8-dihydropteroate by dihydrofolate synthetase.ApplicationsDihydrofolic Acid is an intermediate in mammalian conversion of dietary folic acid to tetrahydrofolate by dihydrofolate reductase (DHFR). Folic acid (FA) and Dihydrofolic acid (FAH2) are substrates of dihydrofolate reductase(s) which reduce them to tetrahydrofolate (THF).

IUPAC Name：(2S)-2-[[4-[(2-amino-4-oxo-7,8-dihydro-3H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid

INCHI：InChI=1S/C19H21N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,12,21H,5-8H2,(H,24,29)(H,27,28)(H,31,32)(H4,20,22,25,26,30)/t12-/m0/s1

InChi Key：OZRNSSUDZOLUSN-LBPRGKRZSA-N

Canonical SMILES：C1C(=NC2=C(N1)N=C(NC2=O)N)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O

Isomeric SMILES：C1C(=NC2=C(N1)N=C(NC2=O)N)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)O

WGK Germany：3

PubChem CID：135398604

PubChem SID：488202821

敏感性：对光线敏感；对空气敏感；易吸潮；对热敏感

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritation

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319

个人防护装备：dust mask type N95 (US), Eyeshields, Gloves

产品包装