产品名称

英文名称：D-(+)-Trehalose dihydrate

同义词

TREHALOSE, DIHYDRATE 、 a-d-glucopyranosyl-a-d-glucopyranoside 、 DPVHGFAJLZWDOC-PVXXTIHASA-N 、 (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-3,4,5-triol;dihydrate、D(+)-海藻糖 、 二水海藻糖 、 α,α-海藻糖 、 α-D-吡喃葡萄糖基-α-D-吡喃葡萄糖苷

产品性质

CAS编号：6138-23-4

分子式：C12H22O11·2H2O

分子量：378.33

Beilstein号：5322018

EC号：202-739-6

MDL号：MFCD00071594

PubChem编号：181978

别名：D(+)-海藻糖 | 二水海藻糖 | α,α-海藻糖 | α-D-吡喃葡萄糖基-α-D-吡喃葡萄糖苷

英文别名：TREHALOSE, DIHYDRATE | a-d-glucopyranosyl-a-d-glucopyranoside | DPVHGFAJLZWDOC-PVXXTIHASA-N | (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-3,4,5-triol;dihydrate

规格或纯度：来自于木薯淀粉, ≥99%

英文名称：D-(+)-Trehalose dihydrate

生化机理：Trehalose is a non-reducing sμgar formed from two glucose units joined by a 1-1 alpha bond. It is thoμght to provide plants and animals with the ability to withstanding periods of dehydration.

应用：An osmolyte, chemical chaperone, and inducer of autophagy. Use as a cryoprotectant in a variety of cell freezing media.

储存温度：充氩

运输条件：常规运输

产品介绍：海藻糖，也称为真菌糖或海藻糖，是一种常见于真菌、细菌和无脊椎动物中的非还原性葡萄糖二糖。它在这些生物中的存在突出了它在各种生物过程中的重要性以及在生化研究和细胞培养研究中的潜在应用。 D-(+)-海藻糖二水合物可用于作为转录因子 EB (TFEB)，研究其对人矽肺肺泡巨噬细胞自噬-溶酶体系统的影响；作为喷雾干燥蛋白质制剂中的稳定赋形剂；作为冷冻保护剂，研究其对小鼠睾丸细胞悬浮液的影响。 D-(+)-海藻糖具有抗干燥和冷冻保存活性。它作为渗透剂和应激保护剂，并有助于碳的储存和运输。海藻糖用于食品、化妆品和制药行业。[6]它对于某些被称为脱水生物的昆虫和植物在高脱水率等恶劣环境下的生存起着至关重要的作用。通过离子交换色谱制备。 Trehalose, Dihydrate, is an osmolyte, a chemical chaperone and inducer of autophagy, that has been reported to protect cells against numerous environmental stresses. This compound contains many properties that allow it to stabilize partially unfolded protein molecules and inhibit protein aggregation. These properties include a low chemical reactivity, high glass transition temperature, existence of numerous polymorphs, nonreducing nature, and high affinity for water molecules. Additionally, Trehalose has been noted to bind to expanded polyglutamines and stabilize partially unfolded polyglutamine-containing proteins.An osmolyte, chemical chaperone, and inducer of autophagy.

IUPAC Name：(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-3,4,5-triol;dihydrate

INCHI：InChI=1S/C12H22O11.2H2O/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12;;/h3-20H,1-2H2;2*1H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-;;/m1../s1

InChi Key：DPVHGFAJLZWDOC-PVXXTIHASA-N

Canonical SMILES：C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)O)O)O)O.O.O

Isomeric SMILES：C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)O)O)O)O)O.O.O

WGK Germany：2

PubChem CID：181978

溶解性：Soluble in water (100 mg/ml), and hot alcohol.

密度：1.76

敏感性：易吸潮

比旋光度：181 ° (C=7, H2O)

熔点：97-99°C

Merck Index：9580

个人防护装备：Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter

产品包装