产品名称

英文名称：Metoclopramide

同义词

metoclopramide、364-62-5、Methochlopramide、Metochlopramide、Metaclopramide、Reliveran、Primperan、Metaclopromide、Elieten、Reglan、Metoclol、Moriperan、Terperan、Plasil、Metoclopramida、Metoclopramidum、2-Methoxy-5-chloroprocainamide、Maxolon、4-Amino-5-chloro-N-(2-(dieth、4-氨基-5-氯-N-[2-(二乙氨基)乙基]-2-甲氧基苯甲酰胺

产品性质

CAS编号：364-62-5

分子式：C14H22ClN3O2

分子量：299.8

Beilstein号：1884366

EC号：206-662-9

MDL号：MFCD00211338

PubChem编号：4168

别名：4-氨基-5-氯-N-[2-(二乙氨基)乙基]-2-甲氧基苯甲酰胺

英文别名：metoclopramide|364-62-5|Methochlopramide|Metochlopramide|Metaclopramide|Reliveran|Primperan|Metaclopromide|Elieten|Reglan|Metoclol|Moriperan|Terperan|Plasil|Metoclopramida|Metoclopramidum|2-Methoxy-5-chloroprocainamide|Maxolon|4-Amino-5-chloro-N-(2-(dieth

规格或纯度：98%

英文名称：Metoclopramide

生化机理：Metoclopramide is a dopamine receptor antagonist which has been used for treatment of a variety of gastrointestinal symptoms over the last thirty years. In various countries, metoclopramide is the antiemetic drμg of choice in pregnant women. Findings provide reassurance regarding the safety of metoclopramide for the fetus when the drμg is given to women to relieve nausea and vomiting during pregnancy. Evidence also supports its use for gastroparesis (poor stomach emptying) and gastroesophageal reflux disease. It appears to bind to dopamine D2 receptors where it is a receptor antagonist, and is also a mixed 5-HT3 receptor antagonist/ 5-HT4 receptor agonist.

储存温度：2-8°C储存

运输条件：冰袋运输

产品介绍：Metoclopramide is a drug, which can be effective in the treatment of severe nausea and vomiting caused by the anticancer drug cis-platinum.Metoclopramide may be used as an analytical reference standard for the determination of the analyte in· Human plasma by liquid-liquid extraction (LLE) with dichloromethane followed by hydrophilic interaction chromatography-electrospray iionization-tandem mass spectrometry (HILIC-ESI-MS/MS) operating in selected reaction monitoring (SRM) mode of detection.Metoclopramide is a drug, which can be effective in the treatment of severe nausea and vomiting caused by the anticancer drug cis-platinum.Metoclopramide may be used as an analytical reference standard for the determination of the analyte in· Human plasma by liquid-liquid extraction (LLE) with dichloromethane followed by hydrophilic interaction chromatography-electrospray iionization-tandem mass spectrometry (HILIC-ESI-MS/MS) operating in selected reaction monitoring (SRM) mode of detection.

IUPAC Name：4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide

INCHI：InChI=1S/C14H22ClN3O2/c1-4-18(5-2)7-6-17-14(19)10-8-11(15)12(16)9-13(10)20-3/h8-9H,4-7,16H2,1-3H3,(H,17,19)

InChi Key：TTWJBBZEZQICBI-UHFFFAOYSA-N

Canonical SMILES：CCN(CC)CCNC(=O)C1=CC(=C(C=C1OC)N)Cl

Isomeric SMILES：CCN(CC)CCNC(=O)C1=CC(=C(C=C1OC)N)Cl

WGK Germany：3

RTECS：BZ3300000

PubChem CID：4168

溶解性：Soluble in water (miscible), and ethanol.

敏感性：对热敏感

熔点：149°C

象形图：

信号词：Danger

危险声明：H302 Harmful if swallowedH370 Causes damage to organsH362 May cause harm to breast-fed children

预防措施声明：P321,P405,P501,P264,P260,P270,P330,P263,P203,P301+P317,P318,P308+P316

产品包装