产品名称

英文名称：Adenine 9-β-D-arabinofuranoside

同义词

Vidarabine、5536-17-4、Adenine arabinoside、Ara-A、Vira-A、Arabinosyladenine、Spongoadenosine、Araadenosine、9-beta-D-Arabinofuranosyladenine、Arasena-A、Vidarabine anhydrous、Arabinosyl adenine、Arabinoside adenine、(2R,3S,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxym

产品性质

CAS编号：5536-17-4

分子式：C10H13N5O4

分子量：267.24

PubChem编号：21704

英文别名：Vidarabine|5536-17-4|Adenine arabinoside|Ara-A|Vira-A|Arabinosyladenine|Spongoadenosine|Araadenosine|9-beta-D-Arabinofuranosyladenine|Arasena-A|Vidarabine anhydrous|Arabinosyl adenine|Arabinoside adenine|(2R,3S,4S,5R)-2-(6-Amino-9H-purin-9-yl)-5-(hydroxym

规格或纯度：99%

英文名称：Adenine 9-β-D-arabinofuranoside

生化机理：抗病毒药（HSV-1的IC 50 = 21μM）。腺苷类似物。抑制病毒DNA的合成。抑制腺苷酸环化酶。血脑屏障通透。体内具有活性

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Adenine 9-β-D-arabinofuranoside (AraA) is a nucleoside analog. It is an antiviral drμg and targets viral DNA polymerases and is majorly used for treating herpes simplex viral infection. It is a potent inhibitor of AMP-activated protein kinase (AMPK).It also inhibits cardiac type 5 adenylyl cyclase but does not improve pathology in cardiovascular diseasesAdenine 9-β-D-arabinofuranoside has been used for the inhibition of 5′ AMP-activated protein kinase (AMPK) in liver, muscle and cardiac cells H9c2.Adenine 9-β-D-arabinofuranoside (AraA) is a nucleoside analog. It is an antiviral drug and targets viral DNA polymerases and is majorly used for treating herpes simplex viral infection. It is a potent inhibitor of AMP-activated protein kinase (AMPK).It also inhibits cardiac type 5 adenylyl cyclase but does not improve pathology in cardiovascular diseases

ALogP：-1.1

IUPAC Name：(2R,3S,4S,5R)-2-(6-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

INCHI：InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7+,10-/m1/s1

InChi Key：OIRDTQYFTABQOQ-UHTZMRCNSA-N

Canonical SMILES：C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)O)N

Isomeric SMILES：C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@H]([C@@H]([C@H](O3)CO)O)O)N

PubChem CID：21704

DrugBank Ligand：DB00194

CAS Registry No.：5536-17-4

Wikipedia：Vidarabine

ChEMBL Ligand：CHEMBL1090

RCSB PDB Ligand：RAB

DrugCentral Ligand：2818

象形图：

信号词：Warning

危险声明：H361 Suspected of damaging fertility or the unborn child

预防措施声明：P280,P405,P501,P203,P318

产品包装