产品名称

英文名称：Cefoperazone

同义词

Cefoperazone [INNBAN]、EINECS 263-749-4、(6R,7R)-7-{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-(4-hydroxyphenyl)acetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)thio]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid、CEFOPERA、头孢哌酮

产品性质

CAS编号：62893-19-0

分子式：C25H27N9O8S2

分子量：645.67

MDL号：MFCD00865067

PubChem编号：44187

别名：头孢哌酮

英文别名：Cefoperazone [INNBAN]|EINECS 263-749-4|(6R,7R)-7-{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-(4-hydroxyphenyl)acetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)thio]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid|CEFOPERA

规格或纯度：≥98%

英文名称：Cefoperazone

生化机理：Cefoperazone Acid is an antimicrobial agent that possesses potent LACTB (β-lactamase) inhibitory properties.Potent β-lactamase inhibitor. Antibiotic agent. Inhibits peptidoglycan synthesis. Active against Pseudomonas. Shows broad spectrum bactericidal effects in vivo.

储存温度：2-8°C储存

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Cefoperazone是一种头孢菌素类抗生素，能抑制rMrp2调节的17βG的吸收[3 H]E2，其IC50是199 μM。An antimicrobial β-lactamase inhibitor.Cefoperazone is a cephalosporin antibiotic for inhibition of rMrp2-mediated [3H]E217βG uptake with IC50 of 199 μM.An antimicrobial β-lactamase inhibitor.

IUPAC Name：(6R,7R)-7-[[(2R)-2-[(4-ethyl-2,3-dioxopiperazine-1-carbonyl)amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

INCHI：InChI=1S/C25H27N9O8S2/c1-3-32-8-9-33(21(39)20(32)38)24(42)27-15(12-4-6-14(35)7-5-12)18(36)26-16-19(37)34-17(23(40)41)13(10-43-22(16)34)11-44-25-28-29-30-31(25)2/h4-7,15-16,22,35H,3,8-11H2,1-2H3,(H,26,36)(H,27,42)(H,40,41)/t15-,16-,22-/m1/s1

InChi Key：GCFBRXLSHGKWDP-XCGNWRKASA-N

Canonical SMILES：CCN1CCN(C(=O)C1=O)C(=O)NC(C2=CC=C(C=C2)O)C(=O)NC3C4N(C3=O)C(=C(CS4)CSC5=NN=NN5C)C(=O)O

Isomeric SMILES：CCN1CCN(C(=O)C1=O)C(=O)N[C@H](C2=CC=C(C=C2)O)C(=O)N[C@H]3[C@@H]4N(C3=O)C(=C(CS4)CSC5=NN=NN5C)C(=O)O

PubChem CID：44187

CAS Registry No.：62893-19-0

ChEBI：CHEBI3493

ChEMBL Ligand：CHEMBL507674

DrugBank Ligand：DB01329

DrugCentral Ligand：543

Wikipedia：Cefoperazone

Antibiotic DB：1909

溶解性：DMSO 129 mg/mL Water <1 mg/mL Ethanol <1 mg/mL

敏感性：对热敏感

熔点：173 °C(dec.)

象形图：

信号词：Danger

危险声明：H317 May cause an allergic skin reactionH334 May cause allergy or asthma symptoms or breathing difficulties if inhaled

预防措施声明：P261,P280,P302+P352,P321,P501,P284,P304+P340,P272,P333+P313,P362+P364,P342+P316

Merck Index：1930

产品包装