产品名称

英文名称：Benfotiamine

同义词

benfotiamine、22457-89-2、S-Benzoylthiamine O-monophosphate、{[(3E)-4-{N-[(4-amino-2-methylpyrimidin-5-yl)methyl]formamido}-3-[(E)-benzoylsulfanyl]pent-3-en-1-yl]oxy}phosphonic acid、NCGC00016764-01、CAS-22457-89-2、Spectrum5_001042、SCHEMBL188071、SPECTRUM150310

产品性质

CAS编号：22457-89-2

分子式：C19H23N4O6PS

分子量：466.45

EC号：245-013-4

MDL号：MFCD00057343

PubChem编号：5282168

英文别名：benfotiamine|22457-89-2|S-Benzoylthiamine O-monophosphate|{[(3E)-4-{N-[(4-amino-2-methylpyrimidin-5-yl)methyl]formamido}-3-[(E)-benzoylsulfanyl]pent-3-en-1-yl]oxy}phosphonic acid|NCGC00016764-01|CAS-22457-89-2|Spectrum5_001042|SCHEMBL188071|SPECTRUM150310

规格或纯度：98.0%

英文名称：Benfotiamine

生化机理：S-Benzoylthiamine O-monophosphate (Benfotiamine) is a therapeutic agent. It helps in the prevention of diabetic complications such as, retinopathy, neuropathy and nephropathy. Benfotiamine inhibits the synthesis of glycation end products (AGEs) in diabetes. Benfotiamine is considered as a nutraceutical product for the prevention of diabetic neuropathy.Vitamin B1 analogue. Potent anti-oxidant. Increases thiamine levels in plasma, erythrocytes and liver cells with greater potency than vitamin B1. Shows antineuropathic effects in vivo. Orally active.

储存温度：2-8°C储存

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：S-苯甲酰基硫胺 O-单磷酸酯（苯磷硫胺）是两亲性 S-酰基硫胺衍生物。是一种脂溶性维生素。苯磷硫胺含噻唑环。与硫胺素相比，苯磷硫胺具有更高的生物利用度。用途S-苯甲酰基硫胺 O-单磷酸酯用于确定其对大鼠骨骼肌缺血和再灌注的影响。S-Benzoylthiamine O-monophosphate (Benfotiamine) is an amphiphilic S-acyl thiamine derivative.It is a lipid-soluble vitamin. Benfotiamine contains a thiazole ring.Benfotiamine has a greater bioavailability than thiamine.S-Benzoylthiamine O-monophosphate has been used to determine its effect on ischemia and reperfusion in skeletal muscles of rat.

IUPAC Name：S-[(E)-2-[(4-amino-2-methylpyrimidin-5-yl)methyl-formylamino]-5-phosphonooxypent-2-en-3-yl] benzenecarbothioate

INCHI：InChI=1S/C19H23N4O6PS/c1-13(23(12-24)11-16-10-21-14(2)22-18(16)20)17(8-9-29-30(26,27)28)31-19(25)15-6-4-3-5-7-15/h3-7,10,12H,8-9,11H2,1-2H3,(H2,20,21,22)(H2,26,27,28)/b17-13+

InChi Key：BTNNPSLJPBRMLZ-GHRIWEEISA-N

Canonical SMILES：CC1=NC=C(C(=N1)N)CN(C=O)C(=C(CCOP(=O)(O)O)SC(=O)C2=CC=CC=C2)C

Isomeric SMILES：CC1=NC=C(C(=N1)N)CN(C=O)/C(=C(\CCOP(=O)(O)O)/SC(=O)C2=CC=CC=C2)/C

PubChem CID：5282168

溶解性：DMSO

敏感性：对热敏感

熔点：192 °C

Merck Index：1041

产品包装