产品名称

英文名称：Geranylgeraniol

同义词

Geranylgeraniol、24034-73-9、Tetraprenol、Geranyl geraniol、(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-ol、(E,E,E)-Geranylgeraniol、trans-Geranylgeraniol、7614-21-3、(E,E,E)-Geranylgeranyl alcohol、Geranylgeranyl alcohol、All-trans-Geranylgeranio、all trans-3,7,11-15-Tetramethyl-2,6,10,14-hexadecatetraen-1-ol、Tetraprenol、Trans,Trans,Trans-Geranylgeraniol、全反式-3,7,11-15-四甲基-2,6,10,14-十六碳四烯-1-醇

产品性质

CAS编号：24034-73-9

分子式：C20H34O

分子量：290.483

PubChem编号：5281365

别名：all trans-3,7,11-15-Tetramethyl-2,6,10,14-hexadecatetraen-1-ol|Tetraprenol|Trans,Trans,Trans-Geranylgeraniol|全反式-3,7,11-15-四甲基-2,6,10,14-十六碳四烯-1-醇

英文别名：Geranylgeraniol|24034-73-9|Tetraprenol|Geranyl geraniol|(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-ol|(E,E,E)-Geranylgeraniol|trans-Geranylgeraniol|7614-21-3|(E,E,E)-Geranylgeranyl alcohol|Geranylgeranyl alcohol|All-trans-Geranylgeranio

规格或纯度：95%

英文名称：Geranylgeraniol

生化机理：As the pyrophosphate, the metabolic precursor of all diterpenes. Screening in vitro shows this to be a potent and selective agent against Mycobacterium tuberculosis.Mevalonate pathway intermediate and geranylgeranylpyrophosphate precursor. Prevents bone re-absorption, inhibition of osteoclast formation, kinase activation and induces apoptosis in vitro. Supresses tumour cell growth in vitro. (IC 50 = 55 µM).

储存温度：-20°C储存,充氩

运输条件：超低温冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Geranylgeraniol, a precursor to geranylgeranylpyrophosphate, is an intermediate in the mevalonate pathway. This compound has been shown to prevent bone re-absorption, inhibition of osteoclast formation, and kinase activation in vitro When working with statins, geranylgeraniol can reduce the toxicity without inhibiting the cholesterol-producing effects. Geranylgeraniol has been documented to counteract the effects of fluvastatin by inhibiting activation of caspase-1 and production of IL-1. It has been found to induce apoptosis in HL-60 cells.香叶基香叶醇本身具有广泛的生理活性，是多种具有生化意义的产物的生化合成前体，如萜类、胡萝卜素、甾体、胆固醇和紫杉醇等。Geranylgeraniol, a precursor to geranylgeranylpyrophosphate, is an intermediate in the mevalonate pathway. This compound has been shown to prevent bone re-absorption, inhibition of osteoclast formation, and kinase activation in vitro When working with statins, geranylgeraniol can reduce the toxicity without inhibiting the cholesterol-producing effects. Geranylgeraniol has been documented to counteract the effects of fluvastatin by inhibiting activation of caspase-1 and production of IL-1. It has been found to induce apoptosis in HL-60 cells.An intermediate in the mevalonate pathway.

IUPAC Name：(2E,6E,10E)-3,7,11,15-tetramethylhexadeca-2,6,10,14-tetraen-1-ol

INCHI：InChI=1S/C20H34O/c1-17(2)9-6-10-18(3)11-7-12-19(4)13-8-14-20(5)15-16-21/h9,11,13,15,21H,6-8,10,12,14,16H2,1-5H3/b18-11+,19-13+,20-15+

InChi Key：OJISWRZIEWCUBN-QIRCYJPOSA-N

Canonical SMILES：CC(=CCCC(=CCCC(=CCCC(=CCO)C)C)C)C

Isomeric SMILES：CC(=CCC/C(=C/CC/C(=C/CC/C(=C/CO)/C)/C)/C)C

PubChem CID：5281365

溶解性：Soluble in DMSO (>25 mg/ml), ethanol (>25 mg/ml), chloroform, dichloromethane, ethyl acetate, hexane, ether, and acetone.

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritation

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319

产品包装