产品名称

英文名称：Etravirine (TMC125)

同义词

Etravirine、269055-15-4、Intelence、TMC125、TMC-125、Etravirine (TMC125)、TMC 125、R165335、R-165335、4-((6-Amino-5-bromo-2-((4-cyanophenyl)amino)pyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile、TMC125 cpd、4-({6-AMINO-5-BROMO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY

产品性质

CAS编号：269055-15-4

分子式：C20H15BrN6O

分子量：435.28

PubChem编号：193962

英文别名：Etravirine|269055-15-4|Intelence|TMC125|TMC-125|Etravirine (TMC125)|TMC 125|R165335|R-165335|4-((6-Amino-5-bromo-2-((4-cyanophenyl)amino)pyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile|TMC125 cpd|4-({6-AMINO-5-BROMO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY

规格或纯度：≥95%

英文名称：Etravirine (TMC125)

生化机理：Etravirine is a novel HIV reverse transcriptase inhibitor useful in treatment of HIV infection.

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：25mg卖完停产，不再备货

ALogP：4.5

PubChem SID：488188569

IUPAC Name：4-[6-amino-5-bromo-2-(4-cyanoanilino)pyrimidin-4-yl]oxy-3,5-dimethylbenzonitrile

INCHI：InChI=1S/C20H15BrN6O/c1-11-7-14(10-23)8-12(2)17(11)28-19-16(21)18(24)26-20(27-19)25-15-5-3-13(9-22)4-6-15/h3-8H,1-2H3,(H3,24,25,26,27)

InChi Key：PYGWGZALEOIKDF-UHFFFAOYSA-N

Canonical SMILES：CC1=CC(=CC(=C1OC2=NC(=NC(=C2Br)N)NC3=CC=C(C=C3)C#N)C)C#N

Isomeric SMILES：CC1=CC(=CC(=C1OC2=NC(=NC(=C2Br)N)NC3=CC=C(C=C3)C#N)C)C#N

PubChem CID：193962

溶解性：DMSO 42 mg/mL Water <1 mg/mL Ethanol <1 mg/mL

敏感性：对热、光线敏感

象形图：

信号词：Warning

危险声明：H413 May cause long lasting harmful effects to aquatic lifeH302 Harmful if swallowed

预防措施声明：P273,P501,P264,P270,P330,P301+P317

产品包装