产品名称

英文名称：Gemifloxacin mesylate

同义词

Gemifloxacin mesylate、Factive、210353-53-0、Gemifioxacin Mesylate、Gemifloxacin mesilate、Gemifloxacin methanesulfonate、Floxguard、Gemixa、LB 20304a、LB-20304a、Gemifloxacin mesylate [USAN]、Gemifloxacin (mesylate)、X4S9F8RL01、204519-65-3、DTXSID7045948、CHEBI53749

产品性质

CAS编号：210353-53-0

分子式：C19H24FN5O7S

分子量：485.49

PubChem编号：9588170

英文别名：Gemifloxacin mesylate|Factive|210353-53-0|Gemifioxacin Mesylate|Gemifloxacin mesilate|Gemifloxacin methanesulfonate|Floxguard|Gemixa|LB 20304a|LB-20304a|Gemifloxacin mesylate [USAN]|Gemifloxacin (mesylate)|X4S9F8RL01|204519-65-3|DTXSID7045948|CHEBI53749|

规格或纯度：98% (HPLC)

英文名称：Gemifloxacin mesylate

生化机理：Gemifloxacin is a broad-spectrum quinolone antibacterial. Fluoroquinolones stabilize DNA strand breaks created by DNA gyrase and topoisomerase IV by binding to the enzyme-DNA complex generating persistent, covalent enzyme–DNA adducts, inhibiting DNA synthesis. Gemifloxacin is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. Gemifloxacin has also been found to inhibit migration and invasion of human colon cancer cells.

储存温度：避光,-20°C储存,充氩

运输条件：超低温冰袋运输

产品介绍：Gemifloxacin mesylate (SB265805 mesylate; LB20304 mesylate)是一种新型氟萘利酮，具有广谱的抗菌活性，并增强对革兰氏阳性需氧菌的抗菌活性。

PubChem SID：488196290

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488196290

IUPAC Name：7-[(4Z)-3-(aminomethyl)-4-methoxyiminopyrrolidin-1-yl]-1-cyclopropyl-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid;methanesulfonic acid

INCHI：InChI=1S/C18H20FN5O4.CH4O3S/c1-28-22-14-8-23(6-9(14)5-20)17-13(19)4-11-15(25)12(18(26)27)7-24(10-2-3-10)16(11)21-17;1-5(2,3)4/h4,7,9-10H,2-3,5-6,8,20H2,1H3,(H,26,27);1H3,(H,2,3,4)/b22-14+;

InChi Key：JIYMVSQRGZEYAX-CWUUNJJBSA-N

Canonical SMILES：CON=C1CN(CC1CN)C2=C(C=C3C(=O)C(=CN(C3=N2)C4CC4)C(=O)O)F.CS(=O)(=O)O

Isomeric SMILES：CO/N=C/1\CN(CC1CN)C2=C(C=C3C(=O)C(=CN(C3=N2)C4CC4)C(=O)O)F.CS(=O)(=O)O

PubChem CID：9588170

溶解性：DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly)

敏感性：对光线和湿度敏感

产品包装