产品名称

英文名称：Dexrazoxane HCl (ICRF-187, ADR-529)

同义词

Dexrazoxane hydrochloride、149003-01-0、Dexrazoxane HCl、Totect、Cardioxane、Cardioxan、Savene、Zinecard、ADR-529 hydrochloride、ICRF-187 hydrochloride、1263283-43-7、ICRF-187、ICRF 187 hydrochloride、Dexrazoxane (Hydrochloride)、(+)-Razoxane hydrochloride、Razoxane hyd、右雷佐生盐酸盐

产品性质

CAS编号：149003-01-0

分子式：C11H16N4O4·HCl

分子量：304.73

PubChem编号：6918223

别名：右雷佐生盐酸盐

英文别名：Dexrazoxane hydrochloride|149003-01-0|Dexrazoxane HCl|Totect|Cardioxane|Cardioxan|Savene|Zinecard|ADR-529 hydrochloride|ICRF-187 hydrochloride|1263283-43-7|ICRF-187|ICRF 187 hydrochloride|Dexrazoxane (Hydrochloride)|(+)-Razoxane hydrochloride|Razoxane hyd

规格或纯度：≥99%

英文名称：Dexrazoxane HCl (ICRF-187, ADR-529)

生化机理：Dexrazoxane hydrochloride is a cardioprotective agent. As a derivative of EDTA, dexrazoxane chelates iron, thus reduce the number of metal ions complexed with anthracycline and, consequently, decrease the formation of superoxide radicals. This agent is used to protect the heart against the cardiotoxic side effects of anthracyclines, such as doxorubicin. It was speculated that dexrazoxane could be used for further investigation to synthesize new antimalarial drμgs. From Wikipedia.Topoisomerase II inhibitor. Intracellular ion chelator. Bridges and stabilizes an interface between two ATPase promoters. Reduces ROS° production and activates the PI3K/Akt survival pathway. Cardioprotective effects when co-administered with doxorubicin (

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Dexrazoxane HCl(ICRF-187, ADR-529)是一种心脏保护剂。Dexrazoxane HCl(ICRF-187, ADR-529) is a cardioprotective agent.

IUPAC Name：4-[(2S)-2-(3,5-dioxopiperazin-1-yl)propyl]piperazine-2,6-dione;hydrochloride

INCHI：InChI=1S/C11H16N4O4.ClH/c1-7(15-5-10(18)13-11(19)6-15)2-14-3-8(16)12-9(17)4-14;/h7H,2-6H2,1H3,(H,12,16,17)(H,13,18,19);1H/t7-;/m0./s1

InChi Key：BIFMNMPSIYHKDN-FJXQXJEOSA-N

Canonical SMILES：CC(CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2.Cl

Isomeric SMILES：C[C@@H](CN1CC(=O)NC(=O)C1)N2CC(=O)NC(=O)C2.Cl

PubChem CID：6918223

溶解性：DMSO 61 mg/mL Water 61 mg/mL Ethanol <1 mg/mL

产品包装