产品名称

英文名称：LX-4211

同义词

A852129、Sotagliflozin (LX4211)、Sotagliflozin (LX-4211)、1018899-04-1、Tox21_501139、UNII-6B4ZBS263Y、(2S,3R,4R,5S,6R)-2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-tetrahydro-6-(methylthio)-2H-pyran-3,4,5-triol;LX4211、DTXSID20144314、SOTAGLIFLOZIN [MI]、AS-35202、INPEFA、索格列净

产品性质

CAS编号：1018899-04-1

分子式：C21H25ClO5S

分子量：424.94

PubChem编号：24831714

别名：索格列净

英文别名：A852129|Sotagliflozin (LX4211)|Sotagliflozin (LX-4211)|1018899-04-1|Tox21_501139|UNII-6B4ZBS263Y|(2S,3R,4R,5S,6R)-2-(3-(4-ethoxybenzyl)-4-chlorophenyl)-tetrahydro-6-(methylthio)-2H-pyran-3,4,5-triol;LX4211|DTXSID20144314|SOTAGLIFLOZIN [MI]|AS-35202|INPEFA

规格或纯度：≥98%

英文名称：LX-4211

生化机理：LX-4211 is a dual SGLT2/1 inhibitor; Antidiabetic agents.

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：LX-4211是SGLT1/2抑制剂，是抗糖尿病剂。Sotagliflozin (LX4211, LP-802034)是一种双重SGLT1/SGLT2抑制剂，IC50分别为 36 nM 和 1.8 nM。LX-4211 is a potent dual SGLT2/1 inhibitor; Antidiabetic agents.

ALogP：3.2

IUPAC Name：(2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-methylsulfanyloxane-3,4,5-triol

INCHI：InChI=1S/C21H25ClO5S/c1-3-26-15-7-4-12(5-8-15)10-14-11-13(6-9-16(14)22)20-18(24)17(23)19(25)21(27-20)28-2/h4-9,11,17-21,23-25H,3,10H2,1-2H3/t17-,18-,19+,20+,21-/m1/s1

InChi Key：QKDRXGFQVGOQKS-CRSSMBPESA-N

Canonical SMILES：CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)C3C(C(C(C(O3)SC)O)O)O)Cl

Isomeric SMILES：CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)SC)O)O)O)Cl

PubChem CID：24831714

ChEMBL Ligand：CHEMBL3039507

CAS Registry No.：1018899-04-1

DrugCentral Ligand：5339

溶解性：DMSO

象形图：

信号词：Warning

危险声明：H351 Suspected of causing cancerH373 Causes damage to organs through prolonged or repeated exposureH413 May cause long lasting harmful effects to aquatic life

预防措施声明：P273,P280,P405,P501,P260,P203,P318,P319

产品包装