产品名称

英文名称：ASC-J9

同义词

ASC-J9、52328-98-0、Dimethylcurcumin、917813-54-8、(1E,4Z,6E)-1,7-bis(3,4-dimethoxyphenyl)-5-hydroxyhepta-1,4,6-trien-3-one、1,7-Bis-(3,4-dimethoxy-phenyl)-5-hydroxy-hepta-1,4,6-trien-3-one、ASCJ-9、1,7-Bis-(3,4-dimethoxyphenyl)-5-hydroxy-hepta-1,4,6-trien-3-one、GO-Y025、ASC J9、GO Y025、二甲基姜黄素

产品性质

CAS编号：52328-98-0

分子式：C23H24O6

分子量：396.43

PubChem编号：6477182

别名：GO-Y025|ASC J9|GO Y025|二甲基姜黄素

英文别名：ASC-J9|52328-98-0|Dimethylcurcumin|917813-54-8|(1E,4Z,6E)-1,7-bis(3,4-dimethoxyphenyl)-5-hydroxyhepta-1,4,6-trien-3-one|1,7-Bis-(3,4-dimethoxy-phenyl)-5-hydroxy-hepta-1,4,6-trien-3-one|ASCJ-9|1,7-Bis-(3,4-dimethoxyphenyl)-5-hydroxy-hepta-1,4,6-trien-3-one

规格或纯度：≥95%

英文名称：ASC-J9

生化机理：ASC-J9, is antitumor agent. ASC-J9 suppresses castration-resistant prostate cancer growth via degradation of full-length and splice variant androgen receptors. Research results sμggested that targeting both fAR- and AR3-mediated PCa growth by ASC-J9 may represent the novel therapeutic approach to suppress castration-resistant PCa. ASC-J9 ameliorates spinal and bulbar muscular atrophy phenotype via degradation of androgen receptor.

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：卖完停产，不再备货

产品介绍：ASC-J9(GO-Y025; Dimethylcurcumin)能抑制全长和剪切型雄激素受体，对前列腺癌有抑制活性。ASC-J9(GO-Y025; Dimethylcurcumin), is antitumor agent; ASC-J9 suppresses castration-resistant prostate cancer growth via degradation of full-length and splice variant androgen receptors.

IUPAC Name：(1E,4Z,6E)-1,7-bis(3,4-dimethoxyphenyl)-5-hydroxyhepta-1,4,6-trien-3-one

INCHI：InChI=1S/C23H24O6/c1-26-20-11-7-16(13-22(20)28-3)5-9-18(24)15-19(25)10-6-17-8-12-21(27-2)23(14-17)29-4/h5-15,24H,1-4H3/b9-5+,10-6+,18-15-

InChi Key：ZMGUKFHHNQMKJI-CIOHCNBKSA-N

Canonical SMILES：COC1=C(C=C(C=C1)C=CC(=CC(=O)C=CC2=CC(=C(C=C2)OC)OC)O)OC

Isomeric SMILES：COC1=C(C=C(C=C1)/C=C/C(=C/C(=O)/C=C/C2=CC(=C(C=C2)OC)OC)/O)OC

PubChem CID：6477182

溶解性：DMSO

密度：1.191

熔点：129-130oC

产品包装