产品名称

英文名称：GSK2636771

同义词

GSK2636771、1372540-25-4、GSK-2636771、2-methyl-1-(2-methyl-3-(trifluoromethyl)benzyl)-6-morpholino-1H-benzo[d]imidazole-4-carboxylic acid、GSK 2636771、DW94IAT0LS、2-methyl-1-[[2-methyl-3-(trifluoromethyl)phenyl]methyl]-6-morpholin-4-ylbenzimidazole-4-carboxyl

产品性质

CAS编号：1372540-25-4

分子式：C22H22F3N3O3

分子量：433.42

PubChem编号：56949517

英文别名：GSK2636771|1372540-25-4|GSK-2636771|2-methyl-1-(2-methyl-3-(trifluoromethyl)benzyl)-6-morpholino-1H-benzo[d]imidazole-4-carboxylic acid|GSK 2636771|DW94IAT0LS|2-methyl-1-[[2-methyl-3-(trifluoromethyl)phenyl]methyl]-6-morpholin-4-ylbenzimidazole-4-carboxyl

规格或纯度：≥98%

英文名称：GSK2636771

生化机理：GSK2636771 is a potent, orally bioavailable, PI3K beta-selective inhibitor, currently in Phase I/II trials.

储存温度：-20°C储存

运输条件：超低温冰袋运输

备注：卖完停产，不再备货

产品介绍：GSK2636771是一种口服生物有效的PI3Kβ选择性抑制剂，对PTEN缺失细胞系敏感。GSK2636771 is a potent, orally bioavailable, PI3Kβ-selective inhibitor, sensitive to PTEN cell lines

ALogP：4

IUPAC Name：2-methyl-1-[[2-methyl-3-(trifluoromethyl)phenyl]methyl]-6-morpholin-4-ylbenzimidazole-4-carboxylic acid

INCHI：InChI=1S/C22H22F3N3O3/c1-13-15(4-3-5-18(13)22(23,24)25)12-28-14(2)26-20-17(21(29)30)10-16(11-19(20)28)27-6-8-31-9-7-27/h3-5,10-11H,6-9,12H2,1-2H3,(H,29,30)

InChi Key：XTKLTGBKIDQGQL-UHFFFAOYSA-N

Canonical SMILES：CC1=C(C=CC=C1C(F)(F)F)CN2C(=NC3=C(C=C(C=C32)N4CCOCC4)C(=O)O)C

Isomeric SMILES：CC1=C(C=CC=C1C(F)(F)F)CN2C(=NC3=C(C=C(C=C32)N4CCOCC4)C(=O)O)C

PubChem CID：56949517

CAS Registry No.：1372540-25-4

ChEMBL Ligand：CHEMBL3188551

溶解性：DMSO 28 mg/mL Water <1 mg/mL Ethanol <1 mg/mL

产品包装