产品名称

英文名称：Lacidipine

同义词

4-[O-[(E)-2-Carboxyvinyl]phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid, 4-tert-butyl diethyl ester、LACIDIPINE [USAN]、MLS000759454、AB01275445-01、CCG-101153、GR43659X、GR-43659X、D04657、diethyl 2,6-dimethyl-4-[2-[(E)-3-[(2-methylpropan-2-yl)ox、拉西地平

产品性质

CAS编号：103890-78-4

分子式：C26H33NO6

分子量：455.54

MDL号：MFCD00865936

PubChem编号：5311217

别名：拉西地平

英文别名：4-[O-[(E)-2-Carboxyvinyl]phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid, 4-tert-butyl diethyl ester|LACIDIPINE [USAN]|MLS000759454|AB01275445-01|CCG-101153|GR43659X|GR-43659X|D04657|diethyl 2,6-dimethyl-4-[2-[(E)-3-[(2-methylpropan-2-yl)ox

规格或纯度：≥98%

英文名称：Lacidipine

生化机理：Lacidipine is a long-acting calcium antagonist that is used in the management of hypertension. Lacidipine is a L-type Ca(2+) channel blocker belonging to 1,4-dihydropyridine class. Also, Lacidipine inhibits ryanodine receptors on the ER membrane that enhances folding, trafficking and lysosomal activity of ERAD (ER-associated degradation) misfolded lysosomal glucocerebrosidase (GS).

储存温度：2-8°C储存

运输条件：冰袋运输

备注：250mg卖完停产，不再备货

产品介绍：Lacidipine 是一种L-型钙离子通道抑制剂。A calcium channel protein inhibitor and blocker.Lacidipine is a L-type calcium channel blocker.A calcium channel protein inhibitor and blocker.

IUPAC Name：diethyl 2,6-dimethyl-4-[2-[(E)-3-[(2-methylpropan-2-yl)oxy]-3-oxoprop-1-enyl]phenyl]-1,4-dihydropyridine-3,5-dicarboxylate

INCHI：InChI=1S/C26H33NO6/c1-8-31-24(29)21-16(3)27-17(4)22(25(30)32-9-2)23(21)19-13-11-10-12-18(19)14-15-20(28)33-26(5,6)7/h10-15,23,27H,8-9H2,1-7H3/b15-14+

InChi Key：GKQPCPXONLDCMU-CCEZHUSRSA-N

Canonical SMILES：CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2C=CC(=O)OC(C)(C)C)C(=O)OCC)C)C

Isomeric SMILES：CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2/C=C/C(=O)OC(C)(C)C)C(=O)OCC)C)C

WGK Germany：3

PubChem CID：5311217

CAS Registry No.：103890-78-4

DrugBank Ligand：DB09236

溶解性：Soluble in Chloroform

敏感性：对热敏感

熔点：179 °C

象形图：

信号词：Warning

危险声明：H302 Harmful if swallowed

预防措施声明：P501,P264,P270,P330,P301+P317

Merck Index：5331

产品包装