产品名称

英文名称：Fluoxetine HCl

同义词

FLUOXETINE HYDROCHLORIDE、56296-78-7、Fluoxetine Hcl、Prozac、59333-67-4、Sarafem、Fluoxeren、Adofen、Fluctin、Lovan、Fontex、Foxetin、Fluox-Puren、Fluneurin、Fluoxetine (hydrochloride)、Affectine、Deproxin、Digassim、Fluctine、Margrilan、Modipran、Pragmaten、Reconcile、Rowexet、氟苯氧丙胺 盐酸盐、140 盐酸盐、(±)-N-甲基-γ-[4-(三氟甲基)苯氧基]苯丙胺 盐酸盐、氟西汀 HCl、N-甲基-3-苯基-3-[4-(三氟甲基)苯氧基]丙胺盐酸盐

产品性质

CAS编号：56296-78-7

分子式：C17H18F3NO·HCl

分子量：345.79

EC号：260-101-2

MDL号：MFCD00214288

PubChem编号：62857

别名：氟苯氧丙胺 盐酸盐|140 盐酸盐|(±)-N-甲基-γ-[4-(三氟甲基)苯氧基]苯丙胺 盐酸盐|氟西汀 HCl|N-甲基-3-苯基-3-[4-(三氟甲基)苯氧基]丙胺盐酸盐

英文别名：FLUOXETINE HYDROCHLORIDE|56296-78-7|Fluoxetine Hcl|Prozac|59333-67-4|Sarafem|Fluoxeren|Adofen|Fluctin|Lovan|Fontex|Foxetin|Fluox-Puren|Fluneurin|Fluoxetine (hydrochloride)|Affectine|Deproxin|Digassim|Fluctine|Margrilan|Modipran|Pragmaten|Reconcile|Rowexet

规格或纯度：≥98%(HPLC)

英文名称：Fluoxetine HCl

生化机理：Fluoxetine is an ST (5-hydroxytryptamine/serotonin/5-HT reuptake) inhibitor. This is a racemic mixture and both R and S enantiomers which are reported to inhibit 5-HT uptake in synaptosomal preparations of rat cerebral cortex. Additionally, Fluoxetine is also noted to increase extracellular levels of 5-HT in several areas of the rat brain as a result of reuptake inhibition. This increase in availability of 5-HT is reported to lead to a decrease in synthesis and turnover of 5-HT.Potent, selective 5-HT reuptake inhibitor. Antidepressant in vivo . Binds to rat and human 5-HT transporters with K i values of 2 and 0.9-20 nM, respectively. Shows around 150-900-fold selectivity over 5-HT 1A , 5-HT 2A , H 1 , α 1 , α 2 -adrenergic and m

储存温度：2-8°C储存

运输条件：冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Fluoxetine HCl是一种抗抑郁剂，选择性抑制5-羟色胺再摄取。An ST (SERT) inhibitor.Fluoxetine is a selective serotonin-reuptake inhibitor (SSRI) at the neuronal membrane, used in the treatment of depression.An ST (SERT) inhibitor.applicationFluoxetine hydrochloride is a selective serotonin reuptake inhibitor. It is used to treat major depressive disorder, bulimia nervosa (an eating disorder) obsessive-compulsive disorder, panic disorder and premenstrual dysphoric disorder (PMDD).product descriptionFluoxetine hydrochloride is a psychotropic agent and one of the initial members of the anti-depressant class of drugs known as selective serotonin-reuptake inhibitors (SSRIs).

PubChem SID：488183615

PubChem SID url：https//pubchem.ncbi.nlm.nih.gov/substance/488183615

IUPAC Name：N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine;hydrochloride

INCHI：InChI=1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H

InChi Key：GIYXAJPCNFJEHY-UHFFFAOYSA-N

Canonical SMILES：CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F.Cl

Isomeric SMILES：CNCCC(C1=CC=CC=C1)OC2=CC=C(C=C2)C(F)(F)F.Cl

WGK Germany：3

RTECS：UI4050000

PubChem CID：62857

Reaxy-Rn：6759273

溶解性：Soluble in water (4 mg/mL), DMSO (>5 mg/mL), acetone, acetonitrile, chloroform, and methanol.

熔点：159 °C

象形图：

信号词：Danger

危险声明：H315 Causes skin irritationH302 Harmful if swallowedH318 Causes serious eye damageH400 Very toxic to aquatic life

预防措施声明：P273,P280,P302+P352,P321,P501,P264,P270,P362+P364,P391,P330,P264+P265,P301+P317,P305+P354+P338,P317,P332+P317

个人防护装备：dust mask type N95 (US), Eyeshields, Faceshields, Gloves

产品包装