产品名称

英文名称：Enasidenib

同义词

Enasidenib、1446502-11-9、AG-221、IDHIFA、CC-90007 Free Base、AG-221 (Enasidenib)、Enasidenib [INN]、enasidenibum、UNII-3T1SS4E7AG、2-Methyl-1-(4-(6-(trifluoromethyl)pyridin-2-yl)-6-(2-(trifluoromethyl)pyridin-4-ylamino)-1,3,5-triazin-2-ylamino)propan-2-ol、3T1SS4E

产品性质

CAS编号：1446502-11-9

分子式：C19H17F6N7O

分子量：473.4

PubChem编号：89683805

英文别名：Enasidenib|1446502-11-9|AG-221|IDHIFA|CC-90007 Free Base|AG-221 (Enasidenib)|Enasidenib [INN]|enasidenibum|UNII-3T1SS4E7AG|2-Methyl-1-(4-(6-(trifluoromethyl)pyridin-2-yl)-6-(2-(trifluoromethyl)pyridin-4-ylamino)-1,3,5-triazin-2-ylamino)propan-2-ol|3T1SS4E

规格或纯度：97%

英文名称：Enasidenib

储存温度：-20°C储存

运输条件：超低温冰袋运输

产品介绍：产品介绍Enasidenib (AG-221) 是一种新型有效的、具有选择性的IDH2突变酶的可逆抑制剂。

IUPAC Name：2-methyl-1-[[4-[6-(trifluoromethyl)pyridin-2-yl]-6-[[2-(trifluoromethyl)pyridin-4-yl]amino]-1,3,5-triazin-2-yl]amino]propan-2-ol

INCHI：InChI=1S/C19H17F6N7O/c1-17(2,33)9-27-15-30-14(11-4-3-5-12(29-11)18(20,21)22)31-16(32-15)28-10-6-7-26-13(8-10)19(23,24)25/h3-8,33H,9H2,1-2H3,(H2,26,27,28,30,31,32)

InChi Key：DYLUUSLLRIQKOE-UHFFFAOYSA-N

Canonical SMILES：CC(C)(CNC1=NC(=NC(=N1)C2=NC(=CC=C2)C(F)(F)F)NC3=CC(=NC=C3)C(F)(F)F)O

Isomeric SMILES：CC(C)(CNC1=NC(=NC(=N1)C2=NC(=CC=C2)C(F)(F)F)NC3=CC(=NC=C3)C(F)(F)F)O

PubChem CID：89683805

CAS Registry No.：1446502-11-9

RCSB PDB Ligand：69Q

DrugCentral Ligand：5251

溶解性：≥47.3 mg/mL in DMSO; insoluble in H2O; ≥22.9 mg/mL in EtOH

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritationH302 Harmful if swallowed

预防措施声明：P305+P351+P338,P280

产品包装