产品名称

英文名称：Cyclophosphamide monohydrate

同义词

Cyclophosphamide monohydrate、6055-19-2、Cyclophosphamide hydrate、Neosar、Endoxan monohydrate、Revimmune、2-(Bis(2-chloroethyl)amino)-1,3,2-oxazaphosphinane 2-oxide hydrate、Cyclophosphamide (hydrate)、Ciclophosphamide hydrat、Ciclofosfamide、Cycloblastin、6055-19-、环磷酰胺、2-[双(2-氯乙基)氨基]四氢-1,3,2-氧杂氮杂磷杂苯-2-氧化物 一水合物

产品性质

CAS编号：6055-19-2

分子式：C7H15Cl2N2O2P·H2O

分子量：279.1

Beilstein号：4678992

EC号：629-456-4,640-398-9

MDL号：MFCD00149395

PubChem编号：22420

别名：环磷酰胺|2-[双(2-氯乙基)氨基]四氢-1,3,2-氧杂氮杂磷杂苯-2-氧化物 一水合物

英文别名：Cyclophosphamide monohydrate|6055-19-2|Cyclophosphamide hydrate|Neosar|Endoxan monohydrate|Revimmune|2-(Bis(2-chloroethyl)amino)-1,3,2-oxazaphosphinane 2-oxide hydrate|Cyclophosphamide (hydrate)|Ciclophosphamide hydrat|Ciclofosfamide|Cycloblastin|6055-19-

规格或纯度：97%

英文名称：Cyclophosphamide monohydrate

储存温度：2-8°C储存,充氩

运输条件：冰袋运输

产品介绍：应用环磷酰胺一水合物用于1、测试其对TC-1肿瘤细胞的抗肿瘤作用；2、多药溶液的组成部分，分离耐药性人伯基特淋巴瘤细胞系；3、检测小鼠肿瘤细胞系的抗肿瘤免疫力Cyclophosphamide monohydrate is an alkylating, cytotoxic agent experimentally shown to crosslink DNA, causing strand breakage and inducing mutations. It is also believed to possess immunosuppressive properties. Cyclophosphamide Monohydrate inhibits ALDH1 (aldehyde dehydrogenase 1) through its degradation product acrolein, as well as induces apoptosis in the rat thymus via the Fas/Fas ligand pathway.An immunosuppressive, cytotoxic apoptosis inducer.

IUPAC Name：N,N-bis(2-chloroethyl)-2-oxo-1,3,2λ5-oxazaphosphinan-2-amine;hydrate

INCHI：InChI=1S/C7H15Cl2N2O2P.H2O/c8-2-5-11(6-3-9)14(12)10-4-1-7-13-14;/h1-7H2,(H,10,12);1H2

InChi Key：PWOQRKCAHTVFLB-UHFFFAOYSA-N

Canonical SMILES：C1CNP(=O)(OC1)N(CCCl)CCCl.O

Isomeric SMILES：C1CNP(=O)(OC1)N(CCCl)CCCl.O

WGK Germany：3

RTECS：RP6157750

关联CAS：6055-19-2,50-18-0 (Parent)

PubChem CID：22420

UN Number：2811

Packing Group：I

MeSH Entry Terms：(+,-)-2-(bis(2-Chloroethyl)amino)tetrahydro-2H-1,3,2-oxazaphosphorine 2-Oxide Monohydrate;B 518;B-518;B518;Cyclophosphamide;Cyclophosphamide Anhydrous;Cyclophosphamide Monohydrate;Cyclophosphamide, (R)-Isomer;Cyclophosphamide, (S)-Isomer;Cyclophosphane;Cy

Reaxy-Rn：8167897

溶解性：Soluble in water (30 mg/ml), ethanol (slightly soluble), benzene (slightly soluble), ethylene glycol (slightly soluble), carbon tetrachloride (slightly soluble), dioxane (slightly soluble), ether (sparingly soluble), acetone (sparingly soluble), alcohol,

敏感性：对热、光线、空气敏感

闪点(℉)：235.4 °F

闪点(℃)：113 °C

沸点：110°C

熔点：49-53°C

象形图：

信号词：Danger

危险声明：H301 Toxic if swallowedH350 May cause cancer

预防措施声明：P280,P321,P405,P501,P264,P270,P330,P203,P301+P316,P318

Class：6.1

Merck Index：2747

个人防护装备：Eyeshields,Faceshields,full-face particle respirator type N100 (US),Gloves,respirator cartridge type N100 (US),type P1 (EN143) respirator filter,type P3 (EN 143) respirator cartridges

产品包装