产品名称

英文名称：Cerulenin

同义词

HMS3649F20、NCGC00163492-01、BSPBio_001276、CS-6992、Z2311575475、(2r,3s)-3-(nona-4,7-dienoyl)oxirane-2-carboxamide、CHEBI94649、HMS1990P17、HY-A0210、SR-05000002362、2-Oxiranecarboxamide, 3-[(4E,7E)-1-oxo-4,7-nonadien-1-yl]-, (2R,3S)-、3-Nona-4,7-dienoyl-oxirane-2、浅蓝菌素

产品性质

CAS编号：17397-89-6

分子式：C12H17NO3

分子量：223.27

Beilstein号：4140423

EC号：241-424-8

MDL号：MFCD00077686

PubChem编号：5282054

别名：浅蓝菌素

英文别名：HMS3649F20|NCGC00163492-01|BSPBio_001276|CS-6992|Z2311575475|(2r,3s)-3-(nona-4,7-dienoyl)oxirane-2-carboxamide|CHEBI94649|HMS1990P17|HY-A0210|SR-05000002362|2-Oxiranecarboxamide, 3-[(4E,7E)-1-oxo-4,7-nonadien-1-yl]-, (2R,3S)-|3-Nona-4,7-dienoyl-oxirane-2

规格或纯度：≥98%

英文名称：Cerulenin

生化机理：Cerulenin, an antibiotic and antifungal, is an inhibitor of fatty acid biosynthesis; in vitro inhibition of HIV-1 proteinase.Antifungal antibiotic. Fatty Acid Synthase (FAS) and steriod biosynthesis inhibitor. Binds covalently to the active center cysteine of the FAS condensing enzyme domain. Induces apoptosis in vivo .

储存温度：-20°C储存,充氩

运输条件：超低温冰袋运输

备注：如果有可能，您尽量在使用的当天配置溶液，并在当天使用完它。但是，如果您需要预先配制储备溶液，我们建议您将溶液等份保存在-20°C的密封小瓶中。通常，它们最多可以使用一个月。在使用前和打开样品瓶之前，我们建议您让您的产品在室温下平衡至少1小时。需要更多关于溶解度，用法和处理的建议吗？请访问我们的常见问题（FAQ）页面以获取更多详细信息。

产品介绍：Cerulenin has broad application in lipid biochemistry as an inhibitor fatty acid and sterol biosynthesis. Cerulenin binds to β-keto-acyl-ACP .synthase blocking the interaction of malonyl CoA. Cerulenin also an inhibits bacterial fatty acid synthesis, acting on the FabH, FabB and FabF condensation enzymes. Cerulenin stimulates fatty acid oxidation and inhibits HMG-CoA synthetase activity.An inhibitor fatty acid and sterol biosynthesisCerulenin has broad application in lipid biochemistry as an inhibitor fatty acid and sterol biosynthesis. Cerulenin binds to β-keto-acyl-ACP .synthase blocking the interaction of malonyl CoA. Cerulenin also an inhibits bacterial fatty acid synthesis, acting on the FabH, FabB and FabF condensation enzymes. Cerulenin stimulates fatty acid oxidation and inhibits HMG-CoA synthetase activity.An inhibitor fatty acid and sterol biosynthesis

IUPAC Name：(2R,3S)-3-[(4E,7E)-nona-4,7-dienoyl]oxirane-2-carboxamide

INCHI：InChI=1S/C12H17NO3/c1-2-3-4-5-6-7-8-9(14)10-11(16-10)12(13)15/h2-3,5-6,10-11H,4,7-8H2,1H3,(H2,13,15)/b3-2+,6-5+/t10-,11-/m1/s1

InChi Key：GVEZIHKRYBHEFX-NQQPLRFYSA-N

Canonical SMILES：CC=CCC=CCCC(=O)C1C(O1)C(=O)N

Isomeric SMILES：C/C=C/C/C=C/CCC(=O)[C@@H]1[C@@H](O1)C(=O)N

WGK Germany：3

RTECS：JR1670000

PubChem CID：5282054

溶解性：Cerulenin is soluble in DMSO, Methanol, Ethanol, Dichloromethane, Acetone, Benzene and most common solvents. Concentrations up to 20 mg/ml can be achieved. Slightly soluble in H2O. Concentrations up to 0.2 mg/ml are achievable. Not soluble in Petrol Ether

密度：1.134

敏感性：对光敏感

象形图：

信号词：Warning

危险声明：H302 Harmful if swallowed

预防措施声明：P501,P264,P270,P330,P301+P317

个人防护装备：dust mask type N95 (US),Eyeshields,Gloves

产品包装