产品名称

英文名称：Eslicarbazepine Acetate

同义词

Eslicarbazepine acetate、236395-14-5、BIA 2-093、Zebinix、Exalief、Stedesa、Aptiom、exelief、Erelib、Pazzul、Eslicarbazepine (acetate)、BIA-2-093、(S)-5-Carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl acetate、SEP-0002093、UNII-BEA68ZVB2K、BEA68ZVB2K、Sep 0002093、Esl、艾司利卡西平醋酸盐

产品性质

CAS编号：236395-14-5

分子式：C17H16N2O3

分子量：296.32

MDL号：MFCD06798333

PubChem编号：179344

别名：艾司利卡西平醋酸盐

英文别名：Eslicarbazepine acetate|236395-14-5|BIA 2-093|Zebinix|Exalief|Stedesa|Aptiom|exelief|Erelib|Pazzul|Eslicarbazepine (acetate)|BIA-2-093|(S)-5-Carbamoyl-10,11-dihydro-5H-dibenzo[b,f]azepin-10-yl acetate|SEP-0002093|UNII-BEA68ZVB2K|BEA68ZVB2K|Sep 0002093|Esl

规格或纯度：≥98%

英文名称：Eslicarbazepine Acetate

生化机理：Blocker of voltage-gated sodium channels; significantly blocks excitatory amino acid (glutamate and aspartate) release.

应用：Eslicarbazepine acetate is an antiepileptic drug.

储存温度：2-8°C储存

运输条件：冰袋运输

备注：卖完停产，不再备货

产品介绍：Eslicarbazepine acetate(ESL)在latrunculin A诱导的癫痫、痉挛、阵发性脑电活动中具有抗痉挛的作用。除了抑制癫痫发作，它还有改善病情的作用，这一作用可能是通过改变过于兴奋的网络发育来实现的Eslicarbazepine acetate is an antiepileptic drμg.Eslicarbazepine acetate(ESL) has Anticonvulsant effects on the development of latrunculin A-induced seizures and paroxysmal EEG activity. ESL may also exhibit disease-modifying effects beyond suppressing just seizure activity, possibly by altering the development of a hyperexcitable network, as evidenced by the suppressed changes in glycine, taurine, glutamate and aspartate concentrations associated with an antiepileptogenic effectEslicarbazepine acetate是一种抗癫痫药物。

ALogP：2

IUPAC Name：[(5S)-11-carbamoyl-5,6-dihydrobenzo[b][1]benzazepin-5-yl] acetate

INCHI：InChI=1S/C17H16N2O3/c1-11(20)22-16-10-12-6-2-4-8-14(12)19(17(18)21)15-9-5-3-7-13(15)16/h2-9,16H,10H2,1H3,(H2,18,21)/t16-/m0/s1

InChi Key：QIALRBLEEWJACW-INIZCTEOSA-N

Canonical SMILES：CC(=O)OC1CC2=CC=CC=C2N(C3=CC=CC=C13)C(=O)N

Isomeric SMILES：CC(=O)O[C@H]1CC2=CC=CC=C2N(C3=CC=CC=C13)C(=O)N

WGK Germany：3

PubChem CID：179344

敏感性：对热敏感

比旋光度：-22° (C=1,Pyridine)

熔点：187 °C

象形图：

信号词：Warning

危险声明：H315 Causes skin irritationH319 Causes serious eye irritationH335 May cause respiratory irritation

预防措施声明：P261,P305+P351+P338,P280,P302+P352,P321,P405,P501,P264,P271,P304+P340,P403+P233,P362+P364,P264+P265,P337+P317,P332+P317,P319

个人防护装备：dust mask type N95 (US), Eyeshields, Gloves

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